Phase 1 · San Francisco area, CA
Phase 1 clinical trials in San Francisco area, CA
83 recruiting studies have a site in the San Francisco area. This page includes nearby cities such as Oakland, Berkeley, San Mateo, Palo Alto.
83 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 1/Phase 2
A Study of AAV9 Gene Therapy in Participants With Canavan Disease (CANaspire Clinical Trial)
Aspa Therapeutics
- Location
- Oakland, CA + 2 other US sites
- Eligibility basics
- Up to age 2
- RecruitingPhase 1/Phase 2
A Study to Assess the Long-term Safety and Clinical Activity of mRNA-3927 in Participants Previously Enrolled in the mRNA-3927-P101 Study
ModernaTX, Inc.
- Location
- Palo Alto, CA + 5 other US sites
- Eligibility basics
- Ages 1+
- RecruitingPhase 1/Phase 2
Multi-center, Open-label, Single-ascending Dose Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCM
Tenaya Therapeutics
- Location
- La Jolla, CA + 4 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1/Phase 2
Open-Label Study of mRNA-3927 in Participants With Propionic Acidemia
ModernaTX, Inc.
- Location
- Los Angeles, CA + 7 other US sites
- Eligibility basics
- Any age listed
- RecruitingPhase 1/Phase 2
A Phase 1/2 Study of NRTX-1001 Neuronal Cell Therapy in Drug-Resistant Bilateral Mesial Temporal Lobe Epilepsy (MTLE)
Neurona Therapeutics
- Location
- Los Angeles, CA + 15 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1/Phase 2
An Extension Study to Evaluate the Long-Term Safety and Clinical Activity of mRNA-3705 in Participants Previously Enrolled in Other Clinical Studies of mRNA-3705
ModernaTX, Inc.
- Location
- Los Angeles, CA + 2 other US sites
- Eligibility basics
- Ages 1+
- RecruitingPhase 1/Phase 2
Treatment of Moderate to Severe Refractory Crohn's Disease
Tr1X, Inc.
- Location
- Sacramento, CA + 12 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1/Phase 2
Safety and Tolerability of RPE Stem Cell-derived RPE(RPESC-RPE) Transplantation in Patients With Dry Age-related Macular Degeneration (AMD)
Luxa Biotechnology, LLC
- Location
- Beverly Hills, CA + 2 other US sites
- Eligibility basics
- Ages 55+
- RecruitingPhase 1
Evaluating the Effect Of Rifaximin on the Gut Microbiota and Metabolome in SIBO Using CapScan®
Envivo Bio Inc
- Location
- Mountain View, CA
- Eligibility basics
- Ages 18–80
- RecruitingPhase 1
Open-label, Dose Escalation Study of Safety and Preliminary Efficacy of TN-401 in Adults With PKP2 Mutation-associated ARVC
Tenaya Therapeutics
- Location
- San Francisco, CA + 6 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1/Phase 2
Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Reduced Ejection Fraction
Sardocor Corp.
- Location
- San Diego, CA + 4 other US sites
- Eligibility basics
- Ages 18–80
Who these studies look for
Phase 1 studies often have narrow eligibility: specific age and weight ranges, no recent participation in another study, no nicotine, and limits on medications. Some Phase 1 studies recruit patients rather than healthy volunteers, so check each listing.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.