Phase 1 · Indianapolis area, IN
Phase 1 clinical trials in Indianapolis area, IN
32 recruiting studies have a site in the Indianapolis area. This page includes nearby cities such as Carmel, Fishers, Greenwood, Avon.
32 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteersEarly Phase 1Overnight stay mentioned
Interaction of CYP2B6 Genotype and Efavirenz With Methadone and Tizanidine PK
Indiana University
- Location
- Indianapolis, IN
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1
Ph 1a/1b Single Ascending Dose and Multiple Ascending Dose Study of ARQ-234
Arcutis Biotherapeutics, Inc.
- Location
- Plainfield, IN + 6 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1/Phase 2
Phase 1/2 Study of Respiratory Syncytial Virus and Human Metapneumovirus (RSV+HMPV) Vaccine Candidate in Adults 60 Years of Age and Older
Sanofi
- Location
- Indianapolis, IN + 49 other US sites
- Eligibility basics
- Ages 60+
- RecruitingHealthy volunteersPhase 1/Phase 2
Harmony-HHT: ATV-1601 in Participants With Hereditary Hemorrhagic Telangiectasia (HHT)
Atavistik Bio, Inc
- Location
- Indianapolis, IN + 5 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1
A Research Study Looking at How Different Doses of Study Medicine (Inno8) Work in the Body of People With Haemophilia A
Novo Nordisk A/S
- Location
- Indianapolis, IN + 4 other US sites
- Eligibility basics
- Ages 18–64 · Men only
- RecruitingHealthy volunteersPhase 1
Hepatic Impairment With Cirrhosis Due to Cholestatic Liver Disease
Zydus Therapeutics Inc.
- Location
- Indianapolis, IN
- Eligibility basics
- Ages 18–80
- RecruitingHealthy volunteersPhase 1
A Study of the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of BCX17725
BioCryst Pharmaceuticals
- Location
- Indianapolis, IN + 4 other US sites
- Eligibility basics
- Ages 12–65
- RecruitingHealthy volunteersPhase 1
A 3-part Study of SYX-5219 in Healthy Volunteers and Participants With Atopic Dermatitis
Sitryx Therapeutics Ltd
- Location
- Plainfield, IN + 5 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1Overnight stay mentioned
Study to Assess the Use of Tezampanel for Opioid Withdrawal Syndrome in Treatment-Seeking Patients With Opioid Use Disorder
Proniras Corporation
- Location
- Indianapolis, IN
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1
Sex Differences in the Response to Abstinence From Alcohol.
Indiana University
- Location
- Indianapolis, IN
- Eligibility basics
- Ages 21–35
- RecruitingPhase 1/Phase 2
A Study to Investigate the Safety and Effectiveness of a Coagulation Factor IX Gene Insertion Therapy (REGV131-LNP1265) in Pediatric, Adolescent and Adult Participants With Hemophilia B
Regeneron Pharmaceuticals
- Location
- Indianapolis, IN + 16 other US sites
- Eligibility basics
- Ages 2+ · Men only
- RecruitingPhase 1
A Study to Evaluate the Safety and Tolerability of ALN-APP in Patients With EOAD
Alnylam Pharmaceuticals
- Location
- Indianapolis, IN
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
An Optimised GA Interventional Trial (Opti-GAIN) to Test if Treatment With CTx001 is Safe and Works for People With Geographic Atrophy (GA)
Complement Therapeutics
- Location
- Carmel, IN + 3 other US sites
- Eligibility basics
- Ages 55+
- RecruitingPhase 1/Phase 2
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of NXT007 in Persons With Severe or Moderate Hemophilia A
Hoffmann-La Roche
- Location
- Indianapolis, IN + 2 other US sites
- Eligibility basics
- Ages 2–59 · Men only
- RecruitingPhase 1
A Phase 1b, Open-Label Study of DISC-3405 in Participants With Sickle Cell Disease (SCD)
Disc Medicine, Inc
- Location
- Indianapolis, IN + 10 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AG-181 in Subjects With Phenylketonuria
Agios Pharmaceuticals, Inc.
- Location
- Indianapolis, IN + 2 other US sites
- Eligibility basics
- Ages 18–69
- RecruitingPhase 1
Study of GS-0415 and How It Works in People With HIV
Gilead Sciences
- Location
- Indianapolis, IN + 14 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1/Phase 2
A First-in-human Study of KK8123 in Adults With X-linked Hypophosphatemia
Kyowa Kirin Co., Ltd.
- Location
- Indianapolis, IN + 3 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1
HCW9302 (Interleukin-2 Fusion Protein) for Alopecia Areata
HCW Biologics
- Location
- Indianapolis, IN + 2 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 1
Evaluate PK & Safety of Saroglitazar in Subjects With Moderate Hepatic Impairment Due to Cholestatic Liver Disease
Zydus Therapeutics Inc.
- Location
- Indianapolis, IN
- Eligibility basics
- Ages 18–80
- RecruitingPhase 1/Phase 2
CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)
COUR Pharmaceutical Development Company, Inc.
- Location
- Indianapolis, IN + 44 other US sites
- Eligibility basics
- Ages 12–35
- RecruitingPhase 1
A Study of VERVE-102 in Patients With Familial Hypercholesterolemia or Premature Coronary Artery Disease
Verve Therapeutics, Inc.
- Location
- Indianapolis, IN + 9 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 1/Phase 2
4D-150 in Patients With Neovascular (Wet) Age-Related Macular Degeneration
4D Molecular Therapeutics
- Location
- Carmel, IN + 19 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 1/Phase 2
Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne
Sanofi Pasteur, a Sanofi Company
- Location
- Indianapolis, IN + 78 other US sites
- Eligibility basics
- Ages 18–45
Who these studies look for
Phase 1 studies often have narrow eligibility: specific age and weight ranges, no recent participation in another study, no nicotine, and limits on medications. Some Phase 1 studies recruit patients rather than healthy volunteers, so check each listing.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.