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RecruitingPhase 2

A Phase 2a Study of SUN-627 in Participants With Non-Active Secondary Progressive and Primary Progressive Multiple Sclerosis (SPMS/PPMS)

Sundance Biosciences, Inc. · NCT07840326

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–70 · All sexes
Healthy volunteers
Not accepted (a condition is required)
Study type
Interventional · Phase 2
Target enrollment
20
US sites recruiting
3
Study start
October 2026
Record last updated
September 25, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The goal of this Phase 2 clinical trial is to investigate the safety and tolerability of SUN-627 in men and women aged 18-70 years old with a diagnosis of non-active SPMS/PPMS.

Being studied: SUN-627; Placebo

Conditions: Primary Progressive Multiple Sclerosis; Primary Progressive MS; Primary Progressive Multiple Sclerosis (PPMS); Secondary Progressive MS (SPMS); Secondary Progressive Multiple Sclerosis (SPMS); Secondary Progressive MS; Non-Active SPMS; Non-Active Secondary Progressive Multiple Sclerosis; Secondary Progressive Multiple Sclerosis With Inflammatory Disease Activity

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Aged 18-70, inclusive
  • Diagnosis of PPMS or non-active SPMS
  • No MS relapses in the past 2 years
  • Evidence that MS has continued to get worse over time
  • A level of disability that fits the study requirements

Exclusion Criteria

  • Use of certain medications or treatments before the study, or need for these treatments during the study
  • Current participation in another research study
  • Certain abnormal heart rhythm findings on ECG or other heart conditions that may increase risk
  • Certain serious or unstable medical conditions that could make the study unsafe
  • Active infection, recent infection, or a history of repeated infections

Additional inclusion and exclusion criteria are outlined in the full study protocol.

Recruiting US locations

Study contacts (from the official record)

  • Chetan Gandhy, MD · 650-442-3187 · clinicaltrials@sundancebio.com
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A Phase 2a Study of SUN-627 in Participants With Non-Active… (NCT07840326) | Bored Studies