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Assessing MB-Spirit for Psychological Well-being

Sara W Lazar · with Harvard Medical School (HMS and HSDM) · NCT07325448

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–50 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
44
US sites recruiting
1
Study start
March 15, 2026
Record last updated
June 11, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The goal of this clinical trial is to test two new behavioral interventions designed to reduce stress and improve spiritual well-being in stressed adults. The main questions it aims to answer are:

  • Can the program decrease stress and improve spiritual well-being?
  • What brain changes accompany participation in the programs?

Participants will

  • Be randomized to either a live online course that meets for 90 minutes every week for 8-weeks, or to a self-paced program. In the self-paced program, participants will receive materials once a week and can work through them at their own pace. Both programs are designed to decrease stress and improve well-being.
  • Complete questionnaires before and after the course.
  • Complete and interview before and after the course.
  • A subset of people will be randomized to complete an MRI scan of their brain before and after the course.

Participants will be randomized to either take the course right away, or be put on a wait-list. Those on the wait-list will undergo the testing at 2 timepoints before they start the program.

Being studied: MB-Spirit; Strong Behaviors for Stress Reduction

Conditions: Stress

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Understands English
  • Able to attend all 8 classes
  • Able to travel to Boston for MRI scans

Exclusion Criteria

  • claustrophobia, pregnancy, head trauma, metallic implants or devices contraindicating MRI, left-handed, conditions that alter cerebral blood flow or metabolism (e.g. stroke), current use of psychotropic medications, lifetime history of suicidality, homicidally, self-destructive acts, schizophrenia or psychosis.

Recruiting US locations

  • 149 13th St

    Boston, MA 02129

    Site contact: Research Coordinator · 617-724-7108 · slazar@mgh.harvard.edu

Study contacts (from the official record)

  • Study Staff · 617-415-8813 · slazar@mgh.harvard.edu
  • Staff · stressreduction@partners.org
All healthy volunteers studies in Massachusetts →
Assessing MB-Spirit for Psychological Well-being (NCT07325448) | Bored Studies