Location · Massachusetts
Clinical trials recruiting in Massachusetts
886 recruiting studies have at least one site in Massachusetts; 358 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in Massachusetts.
886 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteersPhase 1/Phase 2
A Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell Disease
Novartis Pharmaceuticals
- Location
- Boston, MA + 7 other US sites
- Eligibility basics
- Ages 12–55
- RecruitingHealthy volunteersPhase 1
Study to Evaluate the Safety, Pharmacokinetic, and Pharmacodynamic Effects of MY006 in Healthy Volunteers and Patients With Peanut Allergy
Mabylon AG
- Location
- Boston, MA + 7 other US sites
- Eligibility basics
- Ages 12–55
- RecruitingHealthy volunteersPhase 1
Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of HTX-001
Haya Therapeutics, Inc.
- Location
- Boston, MA + 1 other US site
- Eligibility basics
- Ages 18–70
- RecruitingHealthy volunteersPhase 1/Phase 2
Phase 1/2 Study of Respiratory Syncytial Virus and Human Metapneumovirus (RSV+HMPV) Vaccine Candidate in Adults 60 Years of Age and Older
Sanofi
- Location
- Boston, MA + 49 other US sites
- Eligibility basics
- Ages 60+
- RecruitingHealthy volunteersPhase 1/Phase 2
Harmony-HHT: ATV-1601 in Participants With Hereditary Hemorrhagic Telangiectasia (HHT)
Atavistik Bio, Inc
- Location
- Boston, MA + 5 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1/Phase 2
A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease
Bristol-Myers Squibb
- Location
- Boston, MA + 8 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1/Phase 2
A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
Novartis Pharmaceuticals
- Location
- Boston, MA + 18 other US sites
- Eligibility basics
- Ages 18–100
- RecruitingHealthy volunteersPhase 1
Phase 1a Single Ascending Dose Study of MIB-725 in Healthy Adults
Metro International Biotech, LLC
- Location
- Boston, MA
- Eligibility basics
- Ages 19–60
- RecruitingHealthy volunteersPhase 1
Tracing the Metabolic Flux of Orally Administered NAD+ Precursors
Metro International Biotech, LLC
- Location
- Boston, MA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1
Exploratory Clinical Study to Assess Safety and Efficacy of Xenon Gas Inhalation to Control Neuroinflammation
General Biophysics LLC
- Location
- Boston, MA
- Eligibility basics
- Ages 55–75
- RecruitingPhase 1Overnight stay mentioned
A Study of GNTI-122 in Adults Recently Diagnosed With T1D
GentiBio, Inc
- Location
- Boston, MA + 8 other US sites
- Eligibility basics
- Ages 18–55
- RecruitingPhase 1/Phase 2Overnight stay mentioned
Study is to Assess the Safety and Tolerability of VTx-002 in Participants With ALS
Vector Y Therapeutics
- Location
- Boston, MA + 3 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2Overnight stay mentioned
A Study to Investigate Lithium Brain/Plasma Pharmacokinetics and Safety of an AL001 Oral Capsule Compared to a Marketed Immediate-release Lithium Carbonate Capsule in Subjects With Bipolar I Disorder
Alzamend Neuro, Inc.
- Location
- Boston, MA
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1
A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplant
City of Hope Medical Center
- Location
- Boston, MA + 2 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteersPhase 1
A Safety and Immunogenicity Trial of OCU500, ChAd36 Vector Encoding SARS-CoV-2 Spike Vaccine Via Intranasal and Inhalational Routes in Previously Vaccinated Adults
National Institute of Allergy and Infectious Diseases (NIAID)
- Location
- Boston, MA + 4 other US sites
- Eligibility basics
- Ages 18–64
- RecruitingHealthy volunteersPhase 1
Phase 1 Study of CH505 HIV Vaccine Nanoparticles and mRNA Boosters in Healthy Adults
National Institute of Allergy and Infectious Diseases (NIAID)
- Location
- Boston, MA + 1 other US site
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersOvernight stay mentioned
Eating to Adjust the Timing System
Brigham and Women's Hospital
- Location
- Boston, MA
- Eligibility basics
- Ages 18–45
- RecruitingHealthy volunteersOvernight stay mentioned
Can Food Timing Reduce Your Diabetes Risk?
Brigham and Women's Hospital
- Location
- Boston, MA
- Eligibility basics
- Ages 18–45
- RecruitingHealthy volunteersPhase 1/Phase 2
Topical Netarsudil for the Prevention of Proliferative Vitreoretinopathy in Patients With Retinal Detachment
Massachusetts Eye and Ear Infirmary
- Location
- Boston, MA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1
Investigating the Utility of Demyelination Tracer [18F]3F4AP in Controls and Multiple Sclerosis Subjects
Massachusetts General Hospital
- Location
- Boston, MA
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1
A Clinical Study to Investigate the Safety and Immunogenicity of rVSV∆G-SUDV-GP, a Sudan Virus (SUDV) Vaccine for the Prevention of SUDV Disease in Adults in Good General Health
International AIDS Vaccine Initiative
- Location
- Boston, MA + 2 other US sites
- Eligibility basics
- Ages 18–50
- RecruitingHealthy volunteersPhase 1
Clinical Trial to Evaluate the Safety and Immunogenicity of Hiltonol, Poly-ICLC-adjuvanted CD40.HIVRI.Env (VRIPRO) in Adult Participants Who Previously Participated in HVTN 706
National Institute of Allergy and Infectious Diseases (NIAID)
- Location
- Boston, MA + 3 other US sites
- Eligibility basics
- Ages 18–60
- RecruitingHealthy volunteersOvernight stay mentioned
Effect of Physical Activity Pattern on Cardiometabolic Health
Brigham and Women's Hospital
- Location
- Boston, MA
- Eligibility basics
- Ages 18–45
- RecruitingHealthy volunteersPhase 1
Safety and Tolerability Trial of Psilocybin in Healthy Older Adults
University of Colorado, Denver
- Location
- Boston, MA + 5 other US sites
- Eligibility basics
- Ages 65–85