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RecruitingAccepts healthy volunteersEarly Phase 1

Beta3-adrenergic Receptors and Cardiovascular Function in Aging Women

University of Missouri-Columbia · NCT07674680

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–70 · Women only
Healthy volunteers
Accepted
Study type
Interventional · Early Phase 1
Target enrollment
60
US sites recruiting
1
Study start
July 31, 2026
Record last updated
September 10, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

To determine if vascular beta3 adrenergic receptors are present and functional in aging women and can be targeted to attenuate sympathetic vasoconstriction and enhance vascular function in aging women.

Being studied: Placebo; Gemtesa

Conditions: Women; Aging; Menopause

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Healthy women,
  • Assigned female at birth,
  • 18-70 years of age,
  • Body mass index \<18 or ≥30 kg/m2,

Exclusion Criteria

  • Assigned male at birth,
  • Pregnancy,
  • Breastfeeding,
  • History of hormone replacement therapy, chemical menopause, or oophor-ectomy
  • Polycystic ovarian syndrome or Primary ovarian insufficiency,
  • Current smoking/Nicotine use,
  • Blood pressure ≥140/90 mmHg,
  • Increased risk of bleeding, pro-coagulant disorders, clotting disorders, anticoagulation therapy,
  • Nerve/neurologic disease,
  • Cardiovascular, hepatic, renal, respiratory disease,
  • Hypersensitivity to nitroglycerin,
  • Diabetes,
  • Communication barriers,

Recruiting US locations

  • University of Missouri

    Columbia, MO 65211

    Site contact: Jacqueline Limberg Associate Professor · 1-573-882-2544 · limberglab@missouri.edu

Study contacts (from the official record)

  • Jacqueline Limberg Associate Professor · 1-573-882-2544 · limberglab@missouri.edu
All women’s health studies in Missouri →
Beta3-adrenergic Receptors and Cardiovascular Function in Aging Women (NCT07674680) | Bored Studies