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RecruitingAccepts healthy volunteersEarly Phase 1

Sympathetic Vascular Transduction Across the Menopause Transition: Contributing Mechanisms

University of Missouri-Columbia · NCT06787066

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–70 · Women only
Healthy volunteers
Accepted
Study type
Interventional · Early Phase 1
Target enrollment
75
US sites recruiting
1
Study start
July 10, 2025
Record last updated
September 15, 2025

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The investigators aim to assess the interactions between the sympathetic nervous system and the vasculature in women across the menopause transition to better understand why aging women have a higher risk of cardiovascular disease.

Being studied: Propranolol Hydrochloride; Phentolamine Injection

Conditions: Menopause

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Assigned female at birth
  • 18-70 years of age
  • Body mass index (BMI) \<30 kg/m2

Exclusion Criteria

  • Assigned male at birth
  • Pregnancy, breastfeeding
  • Body mass index ≥30 kg/m2
  • Oral hormonal contraception in last 6 months, history of hormone replacement therapy, oophorectomy
  • Current smoking/nicotine use
  • Increased risk of bleeding, pro-coagulant disorders, clotting disorders, anticoagulation therapy
  • Nerve/neurologic disease
  • Cardiovascular, hepatic, renal, respiratory disease
  • Blood pressure ≥140/90 mmHg
  • Diabetes, Polycystic ovarian syndrome
  • Communication barriers
  • Prescription medications

Recruiting US locations

  • University of Missouri

    Columbia, MO 65211

    Site contact: Jacqueline Limberg · 573-882-2544 · limbergj@missouri.edu

Study contacts (from the official record)

  • Jacqueline Limberg, PhD · 573-882-2420 · limbergj@missouri.edu
All women’s health studies in Missouri →
Sympathetic Vascular Transduction Across the Menopause Transition:… (NCT06787066) | Bored Studies