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Brain Stimulation Enhance Post-stroke Walking Survivors and Healthy Adults

The University of Texas Medical Branch, Galveston · with The Claude D. Pepper Older Americans Independence Centers · NCT06191549

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 21–90 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
70
US sites recruiting
1
Study start
May 1, 2025
Record last updated
October 14, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

Recent studies showed that a non-invasive, low-intensity brain stimulation called transcranial direct current stimulation (tDCS) can effectively increase motor neuron excitability in the brain and therefore promotes functional recovery after stroke. Thus, the overall purpose of this research project is to examine the effect of brain stimulation on motor skill learning in stroke survivors.

Being studied: anodal transcranial direct current stimulation (a-tDCS)

Conditions: Cerebral Vascular Accident

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Age between 21 and 90 years
  • Medical history of a unilateral stroke occurring ≥ 6 months prior to enrollment
  • MRI or CT evidence from the imaging report shown that the stroke involves the corticospinal tract
  • Hemiparesis involving the lower extremity (Fugl-Meyer Lower Extremity Motor Test)
  • No passive range of motion limitation in bilateral hips and knees
  • Limitation of ankle passive range of motion to 10 degrees of dorsiflexion or less
  • Visual acuity can be corrected by glasses or contact lens to 20/20
  • Able to walk independently with/without assistant devices for 10 meters
  • Able to maintain standing position without any assistance >= 30 sec (Short Physical Performance Battery)
  • Evaluation of cognitive status: Mini-mental status examination (MMSE) score ≥ 24

Exclusion Criteria

  • Pregnant women
  • MRI or CT evidence of involvement of the basal ganglia or cerebellum, evidence of multiple lesions, or evidence of any other brain damage or tumors
  • Have any metal implants, cardiac pacemakers, or history of seizures
  • Ongoing orthopedic or other neuromuscular disorders that will restrict exercise training
  • Any vestibular dysfunction or unstable angina
  • Significant cognitive deficits (inability to follow a 2-step command) or severe receptive or global aphasia

Recruiting US locations

  • University of Texas Medical Branch

    Galveston, TX 77555

    Site contact: Shih-Chiao Tseng, PT, PhD · 409-772-9555

Study contacts (from the official record)

  • Shih-Chiao Tseng, PhD · 409-772-9555 · shtseng@utmb.edu
All neurology studies in Texas →
Brain Stimulation Enhance Post-stroke Walking Survivors and… (NCT06191549) | Bored Studies