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Cardiac Magnetic Resonance Tissue Characterization in COVID-19 Survivors

Weill Medical College of Cornell University · with National Heart, Lung, and Blood Institute (NHLBI) · NCT05164744

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18+ · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
510
US sites recruiting
3
Study start
July 1, 2021
Record last updated
January 22, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The purpose of this study is to test if visualizing the heart with cardiac MRI/echo will be important in the understanding cardiac function and prediction of cardiopulmonary symptoms, physical effort tolerance, and outcomes in COVID-19 survivors. If successful, the research will allow us to identify the causes of lasting cardiopulmonary symptoms and begin developing cardiac and lung directed therapies accordingly.

Being studied: Cardiac MRI; Echocardiogram; 6-minute walk test; Questionnaire

Conditions: COVID-19 Pneumonia; COVID-19; COVID-19 Respiratory Infection; COVID-19 Acute Respiratory Distress Syndrome; COVID-19 Lower Respiratory Infection; COVID-19 Acute Bronchitis; Coronavirus Disease 2019

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Emergency room presentation and/or hospitalization with COVID-19 infection defined in accordance with established criteria as follows: SAR-CoV2 RT-PCR+ (severe acute respiratory syndrome coronavirus 2 reverse transcription polymerase chain reaction) and at least one of the following symptoms: dyspnea, cough, dysphagia, rhinorrhea, diarrhea, nausea/vomiting, myalgias, fever, syncope/presyncope.

Exclusion criteria

  • Contraindication to CMR (i.e. non-compatible pacemaker/defibrillator) or gadolinium (known hypersensitivity, eGFR (estimated globular filtration rate) \<30 ml/min/1.73m2).
  • Inability to provide informed consent (e.g. cognitive impairment).
  • Unrelated condition (e.g. neoplasm) with life expectancy \<12 months prohibiting follow-up.
  • Patients with contraindications to gadolinium (known or suspected hypersensitivity, glomerular filtration rate \< 30 ml/min/1.73m2) will undergo non-contrast MRI but will not be excluded from this study.
  • Patients with known or suspected pregnancy based on Weill Cornell Radiology intake surveys (reviewed by a clinical RN (registered nurse), as well as research personnel) will be excluded from the protocol.

Recruiting US locations

  • New York Presbyterian-Brooklyn Methodist Hospital

    Brooklyn, NY 11215-3609

    Site contact: Marline Attallah, MD · 2127462627 · CovidHeartStudy@med.cornell.edu

  • New York Presbyterian Queens

    New York, NY 10021

    Site contact: Susan Ingenito · 7186702414 · CovidHeartStudy@med.cornell.edu

  • Weill Cornell Medicine/New-York Presbyterian Hospital

    New York, NY 10021

    Site contact: Elizabeth Manowitz, BS · 2127462627 · elm4036@med.cornell.edu

Study contacts (from the official record)

  • Elizabeth Manowitz, BS · 2127462627 · elm4036@med.cornell.edu
  • Mahniz Reza, BA · 2127462627 · CovidHeartStudy@med.cornell.edu
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Cardiac Magnetic Resonance Tissue Characterization in COVID-19… (NCT05164744) | Bored Studies