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Changes in Inhibition and Valuation After Eating

Icahn School of Medicine at Mount Sinai · with National Institute of Mental Health (NIMH) · NCT05995496

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–45 · Women only
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
150
US sites recruiting
1
Study start
December 12, 2023
Record last updated
February 17, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

An impaired ability to exert control has been implicated in bulimia nervosa (BN), but this impairment may not represent a stable trait or be the most effective focus for treatment. This project aims to understand how predictions and value-based decisions about control may be abnormally influenced by eating in individuals with BN, thereby maintaining cycles of binge eating, purging, and restriction.

Being studied: Fasting state; Fed state; Magnetic Resonance Imaging

Conditions: Bulimia Nervosa

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Female
  • Aged 18 to 45 years
  • Current BMI greater than or equal to 18.5kg/m2 but under 30kg/m2
  • Right-handed
  • English-speaking

Additional Inclusion Criteria for Women with Bulimia Nervosa:

  • Meet DSM-5 criteria for bulimia nervosa

Exclusion Criteria

  • Medical instability
  • Ongoing medical treatment, medical condition, or psychiatric disorder that may interfere with study variables or participation
  • Shift work
  • Pregnancy, planned pregnancy, or lactation during the study period
  • Allergy to any of the ingredients in or unwillingness to consume the standardized meal or unwillingness to drink water during the fasting period
  • Any contraindication for fMRI

Recruiting US locations

  • Center of Excellence in Eating and Weight Disorders at the Icahn School of Medicine at Mount Sinai

    New York, NY 10029

    Site contact: Jiulin Dai, B.S. · 212-824-9561 · jiulin.dai@mssm.edu

Study contacts (from the official record)

  • Riley Macks, B.A. · (212) 824-9545 · riley.macks@mssm.edu
  • Riley Macks · (212) 824-9545 · riley.macks@mssm.edu
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Changes in Inhibition and Valuation After Eating (NCT05995496) | Bored Studies