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RecruitingAccepts healthy volunteers

Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors

Washington University School of Medicine · with Roche Sequencing Solutions, The Foundation for Barnes-Jewish Hospital · NCT04354064

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18+ · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
100
US sites recruiting
1
Study start
May 29, 2019
Record last updated
February 20, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

Earlier detection of disease recurrence will enable greater treatment options and has strong potential to improve patient outcomes. This project is translational and has the potential to lead to future translational research opportunities, including interventional trials in which therapeutic escalation is offered at the early circulating tumor DNA (ctDNA) molecular residual disease (MRD) detection timepoint. Ultimately, the integration of ctDNA into the clinical workflow has the potential to enhance cancer diagnosis, treatment, surveillance, and prognosis, and guide clinical decision-making in this era of personalized precision medicine.

Conditions: Healthy Volunteer; Prostate Cancer; Head and Neck Cancer; Esophageal Cancer; Genitourinary Cancer; Sarcoma; Breast Cancer; Colon Cancer; Gastrointestinal Cancer; Solid Tumor Cancer; Lung Cancer; Skin Cancer; Melanoma

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Eligible healthy donors will be at least 18 years of age.

Exclusion Criteria

  • Healthy donors younger than 18 years of age

Recruiting US locations

  • Washington University School of Medicine

    St Louis, MO 63110

    Site contact: Melissa Reimers, M.D. · 314-362-7249 · cbumb@wustl.edu

Study contacts (from the official record)

  • Melissa Reimers, M.D. · 314-362-7249 · cbumb@wustl.edu
Circulating Tumor DNA (ctDNA) for Early Treatment Response… (NCT04354064) | Bored Studies