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RecruitingAccepts healthy volunteersPhase 4

Clinical and Radiographic Success of MTA vs Biodentine

Geisinger Clinic · NCT04863222

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 2–12 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Phase 4
Target enrollment
646
US sites recruiting
1
Study start
November 12, 2021
Record last updated
December 23, 2025

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The purpose of this prospective study is to compare the clinical and radiographic success of MTA and Biodentine as a medicament in vital pulp therapy in maxillary and mandibular primary molars in a pediatric population. There is limited research currently on Biodentine since it's a novel product. Biodentine is less expensive than MTA and does not cause discoloration like MTA. Biodentine may be an alternative medicament used for vital pulp therapy in primary molars.

Being studied: Biodentine; mineral trioxide aggregate (MTA)

Conditions: Indirect Pulp Cap; Pulpotomy

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Male or female patients ages of 2 to ≤12 years.
  • Bilateral symptomatic or asymptomatic vital primary molars with caries approximating or into the pulp.
  • Patient who need a pulpotomy and/or indirect pulp cap treatments in two or more quadrants.
  • Parents of patients who can provide consent in English.
  • Patients who need treatment in an operating room setting at Geisinger.

Exclusion Criteria

  • Pre-operative radiographic or clinical symptoms associated with irreversible pulpitis or necrotic pulp.
  • Radiographs not displaying furcation region of the tooth.
  • Patients with cardiac conditions who need prophylaxis for infective Endocarditis.
  • Patients with any type of cancer in the past or present.
  • Non-restorable molars.

Recruiting US locations

Study contacts (from the official record)

  • Gayatri Malik, DMD · 570-271-6355 · gmalik1@geisinger.edu
  • Samantha R Crissinger · 570-271-7499 · srcrissinger@geisinger.edu
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Clinical and Radiographic Success of MTA vs Biodentine (NCT04863222) | Bored Studies