Healthy volunteers · Pennsylvania
Studies for healthy volunteers in Pennsylvania
330 studies have at least one recruiting site in Pennsylvania. These studies say in their official record that they accept healthy volunteers. Many are Phase 1 studies that test how a new medicine is absorbed and tolerated; others recruit healthy people as a comparison group alongside patients.
330 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteersPhase 1Overnight stay mentioned
Intralesional 5-Fluorouracil (5FU), Topical Calcipotriene Treatment for SCC
Melissa Pugliano-Mauro
- Location
- Pittsburgh, PA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1/Phase 2
A Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell Disease
Novartis Pharmaceuticals
- Location
- Philadelphia, PA + 7 other US sites
- Eligibility basics
- Ages 12–55
- RecruitingHealthy volunteersPhase 1/Phase 2
Phase 1/2 Study of Respiratory Syncytial Virus and Human Metapneumovirus (RSV+HMPV) Vaccine Candidate in Adults 60 Years of Age and Older
Sanofi
- Location
- Philadelphia, PA + 49 other US sites
- Eligibility basics
- Ages 60+
- RecruitingHealthy volunteersPhase 1
A Research Study Looking at How Different Doses of Study Medicine (Inno8) Work in the Body of People With Haemophilia A
Novo Nordisk A/S
- Location
- Hershey, PA + 4 other US sites
- Eligibility basics
- Ages 18–64 · Men only
- RecruitingHealthy volunteersPhase 1/Phase 2
A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease
Bristol-Myers Squibb
- Location
- Philadelphia, PA + 8 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1
Phase I Study to Assess the Safety and Efficacy of OCU200 for Center-Involved Diabetic Macular Edema (DME)
Ocugen
- Location
- Erie, PA + 4 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1
FIH Study to Evaluate the Tolerability of PF-07832837 in Healthy Adults and Patients
Pfizer
- Location
- Philadelphia, PA + 4 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingHealthy volunteersPhase 1/Phase 2
A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
Novartis Pharmaceuticals
- Location
- Pittsburgh, PA + 18 other US sites
- Eligibility basics
- Ages 18–100
- RecruitingHealthy volunteersPhase 1
A Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SR604 in Two Participants Groups (Part A: Healthy Participants, and Part B: Participants With Hemophilia A or Hemophilia B or Factor VII…
Equilibra Bioscience LLC
- Location
- Hershey, PA + 6 other US sites
- Eligibility basics
- Ages 18–60
- RecruitingHealthy volunteersPhase 1
A 3-part Study of SYX-5219 in Healthy Volunteers and Participants With Atopic Dermatitis
Sitryx Therapeutics Ltd
- Location
- Philadelphia, PA + 5 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1/Phase 2
Study of VGA039 in Healthy Volunteers and Patients With Von Willebrand Disease (VIVID)
Vega Therapeutics, Inc
- Location
- Pittsburgh, PA + 9 other US sites
- Eligibility basics
- Ages 12–60
- RecruitingHealthy volunteersPhase 1
Phase 1 Study of CH505 HIV Vaccine Nanoparticles and mRNA Boosters in Healthy Adults
National Institute of Allergy and Infectious Diseases (NIAID)
- Location
- Pittsburgh, PA + 1 other US site
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersPhase 1
Army-SPRING Army-Suicide Prevention Research
University of Pennsylvania
- Location
- Philadelphia, PA
- Eligibility basics
- Any age listed
- RecruitingHealthy volunteersOvernight stay mentioned
Clinical and Laboratory Study of Methylmalonic Acidemia
National Human Genome Research Institute (NHGRI)
- Location
- Pittsburgh, PA + 1 other US site
- Eligibility basics
- Ages 1 mo–115
- RecruitingHealthy volunteersOvernight stay mentioned
Natural History, Physiology, Microbiome and Biochemistry Studies of Propionic Acidemia
National Human Genome Research Institute (NHGRI)
- Location
- Pittsburgh, PA + 1 other US site
- Eligibility basics
- Ages 1 mo–100
- RecruitingHealthy volunteersPhase 1/Phase 2
Phase I/II Study to Reduce Post-transplantation Cyclophosphamide Dosing for Older or Unfit Patients Undergoing Bone Marrow Transplantation for Hematologic Malignancies
National Cancer Institute (NCI)
- Location
- Philadelphia, PA + 1 other US site
- Eligibility basics
- Ages 12–85
- RecruitingHealthy volunteersPhase 1
Validation of Nanosensor Oxygen Measurement
Children's Hospital of Philadelphia
- Location
- Philadelphia, PA
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1
Imaging Sex Differences in Smoking-Induced Pulmonary Inflammation
University of Pennsylvania
- Location
- Philadelphia, PA
- Eligibility basics
- Ages 18–45
- RecruitingHealthy volunteersPhase 1
Clinical Trial to Evaluate the Safety and Immunogenicity of Hiltonol, Poly-ICLC-adjuvanted CD40.HIVRI.Env (VRIPRO) in Adult Participants Who Previously Participated in HVTN 706
National Institute of Allergy and Infectious Diseases (NIAID)
- Location
- Philadelphia, PA + 3 other US sites
- Eligibility basics
- Ages 18–60
- RecruitingHealthy volunteersEarly Phase 1
Imaging Mitochondrial Complex-I in Alcohol Use Disorder
Rajesh Narendran
- Location
- Pittsburgh, PA
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersEarly Phase 1
Imaging Mitochondrial Complex-I in Cocaine Use Disorder: a [F-18]BCPP-EF PET Study
Rajesh Narendran
- Location
- Pittsburgh, PA
- Eligibility basics
- Ages 18–45
- RecruitingHealthy volunteersEarly Phase 1
Zinc Oxide Versus Petrolatum Following Skin Surgery
Melissa Pugliano-Mauro
- Location
- Pittsburgh, PA, PA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1
A Study of Safety and Drug Levels of ePGT121v1-LS, PGDM1400LS, and VRC07-523LS in Adult Participants Without HIV-1
National Institute of Allergy and Infectious Diseases (NIAID)
- Location
- Philadelphia, PA + 4 other US sites
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersEarly Phase 1
Neoadjuvant Pembrolizumab and Lenvatinib for Renal Cell Carcinoma
Abramson Cancer Center at Penn Medicine
- Location
- Philadelphia, PA
- Eligibility basics
- Ages 18+
Who these studies look for
“Healthy” is decided at screening, not by you. Sites usually check vital signs, blood and urine tests, an ECG, your medications and sometimes your BMI or smoking status. A study can still turn you away for reasons that have nothing to do with being unwell, such as timing or a full roster.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Do healthy volunteer studies pay?
Many do, because volunteers give up time and follow strict schedules, but amounts are set by each study and are usually only confirmed by the research site. When a record states an amount we show the exact wording; otherwise we say compensation is not disclosed.
What happens at a screening visit?
Expect consent paperwork first, then a health questionnaire, vital signs, blood and urine samples and often an ECG. You can ask questions and withdraw at any time, before or after you sign.