Smoking & vaping · Pennsylvania
Smoking and vaping studies in Pennsylvania
11 studies have at least one recruiting site in Pennsylvania. Tobacco research includes quit-smoking and quit-vaping programs, new cessation medicines and studies of how nicotine products affect the body.
11 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteersPhase 1
Imaging Sex Differences in Smoking-Induced Pulmonary Inflammation
University of Pennsylvania
- Location
- Philadelphia, PA
- Eligibility basics
- Ages 18–45
- RecruitingHealthy volunteers
A Study to Determine the Effects of ENDS Flavor Availability on Abstinence Within Smokers
RAI Services Company
- Location
- Philadelphia, PA + 6 other US sites
- Eligibility basics
- Ages 21–65
- RecruitingPhase 3
Studying NMDA and Sigma-1 in Smoking Cessation Treatment (SUMMIT)
Axsome Therapeutics, Inc.
- Location
- Duncansville, PA + 24 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteers
Use of Nicotine Pouches Among Daily Smokers
Milton S. Hershey Medical Center
- Location
- Hershey, PA + 1 other US site
- Eligibility basics
- Ages 21–70
- RecruitingHealthy volunteers
Testing ANSOS for Efficacy in Multi-Tribal Urban Communities
Lehigh University
- Location
- Bethlehem, PA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Catalyzing Cigarette Smoking Cessation Through Harm Reduction Sampling Among People Unmotivated to Quit
Abramson Cancer Center at Penn Medicine
- Location
- Philadelphia, PA
- Eligibility basics
- Ages 21+
- RecruitingHealthy volunteers
Support and Outreach to Increase Screening for Lung Cancer in Patients With a History of Smoking
Ronald Myers
- Location
- Philadelphia, PA
- Eligibility basics
- Ages 50–77
- RecruitingHealthy volunteers
Linking Brain Network Dynamics to Imminent Smoking Lapse Risk and Behavior
Penn State University
- Location
- University Park, PA
- Eligibility basics
- Ages 21–65
- RecruitingHealthy volunteers
Noncombustible Nicotine Delivery Systems as Potential Harm Reduction Tools for Persistent Cigarette Smokers
Abramson Cancer Center at Penn Medicine
- Location
- Philadelphia, PA
- Eligibility basics
- Ages 21+
- RecruitingHealthy volunteers
Non-invasive Vagus Nerve Stimulation (nVNS) and Cognition in Young Adult Vapers - A Pilot Study
Temple University
- Location
- Philadelphia, PA
- Eligibility basics
- Ages 18–25
- RecruitingHealthy volunteers
The Role of Flavor in the Substitutability of E-cigarettes for Combustible Cigarettes Among Persistent Smokers
Abramson Cancer Center at Penn Medicine
- Location
- Philadelphia, PA
- Eligibility basics
- Ages 21+
Who these studies look for
Most require current smoking or vaping at a set level, measured at screening. Quit studies often include counseling.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Do I have to quit to join?
Cessation studies are for people who want to quit. Other tobacco studies may ask you to keep your usual habits or switch products for a period. The listing explains which.