Cognitive Neurocomputational Task Reliability and Clinical Applications Consortium: Study 3
Washington University School of Medicine · with National Institute of Mental Health (NIMH), University of Minnesota · NCT07900893
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 18–59 · All sexes
- Healthy volunteers
- Accepted
- Study type
- Interventional · Not applicable
- Target enrollment
- 10000
- US sites recruiting
- 2
- Study start
- December 1, 2026
- Record last updated
- October 28, 2026
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
In Study 3, all tasks and models from Aim 1 will be evaluated in a large community sample of online participants recruited through Prolific.
Aim 3 will establish 1) requirements for testing computational algorithms in population-based samples, 2) whether task length is optimal, and 3) whether computational parameters help predict psychopathology (hallucinations and delusions in particular) in the general population, and how these predictors may be impacted by demographic variables, such as race, ethnicity, gender, age and other social determinants of health.
Participant demographics will be matched to the U.S. Census 2023 American Community Survey (ACS) data release (updated as available). MPI MacDonald has successfully recruited large online samples for over a decade.
Specifically, researchers will recruit two samples of n=2,000 to preregister hypotheses and then n=3,000 to independently confirm those hypotheses. Multiple methods will affirm the highest quality human self-report and behavioral data for online samples.
Researchers use Prolific, which is known for high quality research participation, maintaining low levels of bots through strategies such as requiring a photo ID and a waiting period. Second, inclusion criteria will require an approval rating of 90-100% from previous researchers. Participants will complete three sessions, each limited to \~60 min to avoid burnout.
Being studied: Motion Perception Task; Sine Wave Speech Task; Volatility Task; Choice Probabilistic Reversal Task; Kamin Blocking Task; Minnesota Trust Game; Dynamic Trust Game
Conditions: Schizophrenia / Schizoaffective Disorder; SCHIZOPHRENIA 1 (Disorder); Healthy Adult
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Inclusion Criteria
- Residents of the U.S.
- between 18-59 years of age
Exclusion Criteria
- Resides outside of U.S.
- under 18 or over 59 years of age
Recruiting US locations
University of Minnesota
Minneapolis, MN 55455
Site contact: Angus MacDonald III, PhD · 612-624-3813 · angus@umn.edu
Washington University
St Louis, MO 63130
Site contact: Deanna Barch, PhD · 314-935-8729 · dbarch@wustl.edu
Study contacts (from the official record)
- Deanna Barch, PhD · 314-935-8729 · dbarch@wustl.edu
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