Mental health · Minnesota
Mental health studies in Minnesota
18 studies have at least one recruiting site in Minnesota. Mental health research includes studies of depression, anxiety, PTSD, bipolar disorder, schizophrenia and ADHD, testing medicines, devices and talk therapies.
18 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteers
Observational Study of Decentralized Urine Optical Interaction Patterns Associated With Environmental Microplastic and Nanoplastic Exposure
Ecotera Health LLC
- Location
- Minneapolis, MN + 50 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2/Phase 3
Redefine Study: A Study Evaluating the Efficacy, Safety, and Tolerability of COMP360 in Participants With Post-traumatic Stress Disorder
COMPASS Pathways
- Location
- Eden Prairie, MN + 8 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With…
LivaNova
- Location
- Minneapolis, MN + 49 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)
Abbott Medical Devices
- Location
- Minneapolis, MN + 24 other US sites
- Eligibility basics
- Ages 22–70
- RecruitingPhase 3
A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder
Cybin IRL Limited
- Location
- Eden Prairie, MN + 27 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of Esketamine for Reduction of Symptoms of Major Depressive Disorder
Janssen Research & Development, LLC
- Location
- Rochester, MN + 9 other US sites
- Eligibility basics
- Ages 12–17
- RecruitingPhase 2
A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)
atai Therapeutics, Inc.
- Location
- Eden Prairie, MN + 33 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteers
Cognitive Neurocomputational Task Reliability & Clinical Applications Consortium (CNTRACS): Study 1
Washington University School of Medicine
- Location
- Minneapolis, MN + 4 other US sites
- Eligibility basics
- Ages 18–59
- RecruitingHealthy volunteers
State Representation in Early Psychosis 2
University of Minnesota
- Location
- Minneapolis, MN + 1 other US site
- Eligibility basics
- Ages 15–45
- RecruitingHealthy volunteers
Transdiagnostic Cognitive Biomarkers
University of Minnesota
- Location
- Minneapolis, MN
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 2
Parenting in 2 Worlds Multisite Trial
Arizona State University
- Location
- Saint Paul, MN + 3 other US sites
- Eligibility basics
- Ages 12+
- RecruitingHealthy volunteersPhase 4
Pimavanserin vs. Quetiapine for Treatment of Parkinson's Psychosis
VA Office of Research and Development
- Location
- Minneapolis, MN + 8 other US sites
- Eligibility basics
- Ages 40+
- RecruitingHealthy volunteers
Breathing Practice for Brain and Mental Health in Cancer and Neurodegenerative Diseases
Mayo Clinic
- Location
- Rochester, MN
- Eligibility basics
- Ages 18–85
- RecruitingHealthy volunteers
Cognitive and Affective Processes Online
University of Minnesota
- Location
- Minneapolis, MN
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Just-in-Time Training for Youth Mentors
University of Minnesota
- Location
- Minneapolis, MN
- Eligibility basics
- Ages 12+
- RecruitingHealthy volunteersPhase 2
Gii'Igoshimong: Sitting With Your First Family
Johns Hopkins Bloomberg School of Public Health
- Location
- Duluth, MN
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 3
Cognitive Strategies in Early Psychosis 1
University of Minnesota
- Location
- Minneapolis, MN
- Eligibility basics
- Ages 18–35
- RecruitingHealthy volunteers
Mindfulness and Meditation Based Lactation Education on Maternal Breastmilk in the Neonatal ICU
Mayo Clinic
- Location
- Rochester, MN
- Eligibility basics
- Ages 20+ · Women only
Who these studies look for
Studies usually require a confirmed diagnosis and stable circumstances, and they monitor safety closely. If you are in crisis, contact a crisis line or emergency services rather than a study.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Will joining affect my current treatment?
Some studies require changes to medicines, which the study team manages; others add to your usual care. Talk to your own clinician before making any change.