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RecruitingAccepts healthy volunteersPhase 4

Combined Anabolic Therapy

Massachusetts General Hospital · with National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) · NCT06558188

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 45+ · Women only
Healthy volunteers
Accepted
Study type
Interventional · Phase 4
Target enrollment
50
US sites recruiting
1
Study start
February 3, 2025
Record last updated
October 8, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

In this research study the study investigators want to learn more about the effect of two different FDA-approved medication regimens in the treatment of postmenopausal osteoporosis.

Being studied: Romosozumab; Teriparatide

Conditions: Osteoporosis, Postmenopausal; Osteoporosis

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • women aged 45+
  • postmenopausal
  • osteoporotic with high risk of fracture

Exclusion Criteria

  • no significant previous use of bone health modifying treatments
  • known congenital or acquired bone disease other than osteoporosis
  • significant renal disease, liver disease, cardiopulmonary disease, or psychiatric disease
  • abnormal calcium or parathyroid hormone level
  • serum vitamin D \<20 ng/dL
  • anemia (hematocrit \<32%)
  • history of malignancy (except non-melanoma skin carcinoma)
  • excessive alcohol use or substance abuse
  • known contraindications to romosozumab or teriparatide

Recruiting US locations

  • Massachusetts General Hospital

    Boston, MA 02114

    Site contact: Aparna Patnaik, BA · 617-726-6129 · apatnaik1@mgh.harvard.edu

Study contacts (from the official record)

  • Aparna Patnaik, BA · 617-726-6129 · apatnaik1@mgh.harvard.edu
All women’s health studies in Massachusetts →
Combined Anabolic Therapy (NCT06558188) | Bored Studies