RecruitingAccepts healthy volunteers
Comparison of Root Canal Desinfection Protocols
State University of New York at Buffalo · NCT07439614
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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 18–70 · All sexes
- Healthy volunteers
- Accepted
- Study type
- Interventional · Not applicable
- Target enrollment
- 50
- US sites recruiting
- 1
- Study start
- April 1, 2026
- Record last updated
- June 23, 2026
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
Evaluate and compare the disinfecting efficacy of two supplementary antimicrobial protocols in teeth with apical periodontitis
Being studied: Desinfection device; Analytical microbiological methods
Conditions: Periapical Periodontitis
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Inclusion Criteria
- Adult patients able to give informed consent and willing/able to comply with study procedures and follow-up.
- Molar teeth indicated for endodontic treatment.
- Teeth with intact pulp-chamber walls (no extensive coronal destruction).
- Necrotic pulp confirmed by pulp testing.
- Clinical and radiographic evidence of asymptomatic apical periodontitis.
Exclusion Criteria
- Immature teeth
- Teeth with calcified or obliterated canals
- Teeth with extensive coronal destruction
- Teeth with previous endodontic treatment
- Symptomatic apical periodontitis
- Teeth with periodontal pockets greater than 4 mm
- Patients who have received systemic antibiotics in the last 3 months
- Patients with a history of diabetes or immune impairment
- Pregnant patients
Recruiting US locations
Advance Education in Endodontics Program
Buffalo, NY 14214
Study contacts (from the official record)
- Stephen Lyon, DDS · (716) 829-6229 · smlyon@buffalo.edu
- Thamyres Monteiro, MSc · (716) 829-6199 · thamyres@buffalo.edu
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