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Cortical Excitability in Cyclic Vomiting Syndrome

University of Pittsburgh · NCT05256160

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–60 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
110
US sites recruiting
1
Study start
May 16, 2022
Record last updated
August 14, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

This exploratory study will determine if there are differences in cortical excitability between patients suffering from cyclic vomiting syndrome (CVS) and healthy control subjects, as assessed by a non-invasive method of brain stimulation (Transcranial Magnetic Stimulation, TMS).

Being studied: TMS Paired-Pulse assessment of cortical excitability; Autonomic activity

Conditions: Cyclic Vomiting Syndrome

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • diagnosis of CVS

Exclusion Criteria

  • history of CVS (for healthy control population only)
  • psychosis or altered cognitive status
  • history of head injury, metal in the skull, stroke, or a history of seizures or a history of syncope (fainting or passing out)
  • implantable devices, such as a pacemaker or nerve stimulator
  • current use of the following medications or use of substances which are known to lower the seizure threshold: clozapine (Clozaril), chlorpromazine (Thorazine), amphetamines or methamphetamine, Ecstasy, Ketamine, Angel Dust/PCP, cocaine, or 3 or more alcoholic drinks per day
  • pregnancy

Recruiting US locations

Study contacts (from the official record)

  • Elijah D Wright · 412-647-1228 · edw87@pitt.edu
  • David J Levinthal, MD PhD · 412-303-0525 · levinthald@upmc.edu
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Cortical Excitability in Cyclic Vomiting Syndrome (NCT05256160) | Bored Studies