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RecruitingAccepts healthy volunteersEarly Phase 1

Curcumin and EGCG Supplementation to Improve Serum BDNF and Mood Disturbance

Auburn University · NCT06531863

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–50 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Early Phase 1
Target enrollment
64
US sites recruiting
1
Study start
September 30, 2024
Record last updated
February 14, 2025

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The goal of this randomized placebo controlled trial is to examine mood disturbance and serum brain derived neurotrophic factor (BDNF) in people (age 18-50) with DASS-21 subscale scores >9. The main questions it aims to answer are:

Does curcumin and EGCG supplementation improve mood disturbance symptomology? Does curcumin and EGCG supplementation increase serum BDNF? Researchers will compare intervention versus placebo.

Participants will consume an 8-week supplement of both:

  • 1,330mg/day curcumin
  • 350mg/day epigallocatechin gallate (EGCG)

Being studied: Curcumin; Epigallocatechin Gallate; Placebo

Conditions: Mood Disturbance

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Adults age 18-50
  • Depression subscale score of >9/21 on the DASS-21
  • No change in medications or supplements over the past 3 months
  • Can read and speak English

Exclusion Criteria

  • Currently consume curcumin or green tea daily
  • Currently, pregnant, nursing, or trying to become pregnant
  • Currently diagnosed with a perimenopausal disorder

Recruiting US locations

  • Auburn University School of Kinesiology

    Auburn, AL 36849

    Site contact: Drew Fruge, PhD · 3448448433 · adf0003@auburn.edu

Study contacts (from the official record)

  • Aidan Cavanah, MSc · 2057893258 · amc0108@auburn.edu
  • Andrew Fruge, PhD · adf0003@auburn.edu
All healthy volunteers studies in Alabama →
Curcumin and EGCG Supplementation to Improve Serum BDNF and Mood… (NCT06531863) | Bored Studies