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Dairy Choline Bioavailability

University of Wisconsin, Madison · NCT06902480

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Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 51–70 · Women only
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
24
US sites recruiting
1
Study start
September 18, 2026
Record last updated
September 29, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The goal of this clinical trial is to find out if dairy is a good source of choline compared to eggs. The main questions it aims to answer are:

  • How the body uses choline; and,
  • What effect WPPC has on choline metabolism.

Researchers will compare Whey Protein Phospholipid Concentrate (WPPC) to whole egg powder to see if WPPC is as effective as eggs.

Participants will drink a chocolate-flavored smoothie mixed with either WPPC or whole egg powder.

Being studied: WPPC; Whole egg powder

Conditions: Post-menopausal Women; Post-menopausal Status

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Ages between 51 and 70
  • Is currently post-menopausal (Post-menopausal is a term used to describe the time in a woman's life after she has gone through menopause. This usually happens between the ages of 45 and 55. Menopause is when a woman's menstrual periods stop permanently (at least 12 months))
  • Not allergic to the intervention foods and allergens that are related to the production of intervention foods (e.g. dairy products, egg, fish, peanut, shellfish, soy, tree nuts, wheat, crustaceans, gluten, mollusks, mustard, sesame seeds.)
  • Had stable body weight (± 5%) for the past 6 months
  • Free from cancer
  • Did not have weight loss surgery, colon surgery
  • Do not have chronic kidney diseases
  • Do not have malabsorption towards fat and dairy products
  • Willing to complete health surveys
  • Willing to complete two 4-day food diaries
  • Willing to consume the intervention smoothies
  • Willing to provide blood, urine, fecal samples at baseline and after 10 days of intervention

Exclusion Criteria

  • On weight loss/weight gain diets
  • Diagnosed with fat malabsorption
  • Undergoing weight loss surgery
  • Diagnosed with chronic kidney diseases
  • Allergic to the intervention foods and allergens that are related to the production of intervention foods (e.g. dairy products, egg, chocolate, fish, peanut, shellfish, soy, tree nuts, wheat, crustaceans, gluten, mollusks, mustard, sesame seeds, banana, strawberry, raspberry, blackberry, blueberry.)
  • Regularly using antibiotics or probiotics or prebiotics
  • Regularly using weight-loss drugs (GLP-1, Orlistat, Cetilistat, etc.)
  • Regularly using laxatives
  • Unable to avoid strenuous exercise during the study (>4 h vigorous exercise per day)

Recruiting US locations

  • University of Wisconsin - Madison

    Madison, WI 53705

    Site contact: Kevin Shih · sshih22@wisc.edu

Study contacts (from the official record)

  • Kevin Shih · 919-338-9453 · sshih22@wisc.edu
Dairy Choline Bioavailability (NCT06902480) | Bored Studies