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Developing a New MRI Technique to Understand Changes in Brain Tumors After Treatment

Memorial Sloan Kettering Cancer Center · NCT05559853

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18+ · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
119
US sites recruiting
1
Study start
September 22, 2022
Record last updated
March 6, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The purpose of this study is to develop and test a new magnetic resonance imaging (MRI) technique to see if it can be used to tell the difference between tumor growth from worsening of cancer and growth from the effects of treatment in participants who have brain tumors treated with radiation therapy called stereotactic radiosurgery (SRS).

Being studied: CEST-MRF

Conditions: Brain Metastases; Brain Metastases, Adult; Metastatic Brain Tumor; Metastatic Brain Cancer

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

Healthy volunteers [for Study Aim 1 (SA1) and Study Aim 2 (SA2)] will be entered into the study if they meet the following criteria:

  • Age ≥ 18 years
  • Able to understand and give informed consent
  • No known cancer diagnosis

Patients [for Study Aim 1 (SA1)] will be entered into the study if they meet the following criteria:

  • Age ≥ 18 years
  • Able to understand and give informed consent
  • At least one untreated brain metastasis > 1cm (e.g., an enhancing lesion in the brain of a patient with known systemic cancer determined likely to represent metastasis by neuroradiologist)

Patients [for Study Aim 3 (SA3)] will be entered into the study if they meet the following criteria:

  • Age ≥ 18 years
  • Able to understand and give informed consent
  • At least one untreated brain metastasis > 1cm (e.g., an enhancing lesion in the brain of a patient with known systemic cancer determined likely to represent metastasis by neuroradiologist)
  • Planned SRS treatment

Exclusion Criteria

Healthy volunteers (SA1 \& SA2) and patients (SA1 \& SA3) exclusion criteria:

  • Pregnant or breastfeeding women
  • Pre-existing medical conditions, including the likelihood of developing seizures or claustrophobic reactions, and any greater than normal potential for cardiac arrest
  • Age \< 18 years

Recruiting US locations

  • Memorial Sloan Kettering Cancer Center (All Protocol Activities)

    New York, NY 10065

    Site contact: Ouri Coheb, PhD · 646-608-8259 · coheno1@mskcc.org

Study contacts (from the official record)

  • Ouri Cohen, PhD · 646-608-8259 · coheno1@mskcc.org
  • Nelson Moss, MD · 212-639-7075 · mossn@mskcc.org
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Developing a New MRI Technique to Understand Changes in Brain… (NCT05559853) | Bored Studies