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Diet Synergy in Muscle Protein Synthesis

University of Illinois at Urbana-Champaign · NCT07367854

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 19–40 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
15
US sites recruiting
1
Study start
March 1, 2026
Record last updated
May 1, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

In the present semi-crossover randomized design, 15 recreationally active young adults (19-40 y) will receive stable isotope tracer infusions and perform a single bout of resistance exercise. Immediately after exercise, participants will ingest either 1 medium russet potato with skins and 2 ounce-equivalent lean ground beef combination (274 kcals, 19.3 g protein, 5 g fat, 37 g carbohydrates, and 4 g fiber), 2 slices of white bread and beef combination (262 kcals, 19.8 g protein, 6.8 g fat, 28 g carbohydrates, and 1.8 g fiber) or 2 ounce-equivalent beef (93% lean meat/7% fat; 110 kcals, 14.8 g protein, and 5 g fat). Repeated blood and muscle biopsies will be collected to determine whole body leucine kinetics, amino acid concentrations, anabolic signaling and myofibrillar protein synthesis rates during the trials.

Being studied: Resistance Exercise; Potato and Beef; Bread and Beef; Beef

Conditions: Muscle Protein Synthetic Response to Protein; Muscle Protein Synthesis; Muscle Health; Protein Metabolism; Recreational Activities; Isotope Labeling

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Age 19-40 yrs
  • Pre-menopausal
  • Recreationally-active
  • Weight stable for prior 6 months

Exclusion Criteria

  • Age outside of range (20 - 35 yrs)
  • Pregnancy
  • Irregular menstrual cycles (i.e., \~21 day or \~35 day cycle)
  • Participation in previous research using L-[1-13C] leucine and L-[ring-2H5] phenylalanine
  • Participation in other ongoing research that interferes with this study (e.g., conflicting diet, activity interventions, etc.)

Recruiting US locations

  • Louise Freer Hall

    Urbana, IL 61801

    Site contact: Calvin Wei-Ting Chen · 2173906655 · cw148@illinois.edu

Study contacts (from the official record)

  • Nicholas A Burd (Full Professor), PhD · 2172440970 · naburd@illinois.edu
  • Calvin Chen, PhD Student · 2173906655 · cw148@illinois.edu
All nutrition & metabolism studies in Illinois →
Diet Synergy in Muscle Protein Synthesis (NCT07367854) | Bored Studies