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DXA Study of Precision and Reliability

Penn State University · NCT03621306

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18+ · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
400
US sites recruiting
1
Study start
June 16, 2008
Record last updated
July 6, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The purpose of the study is to assess precision of the GE Lunar iDXA, Hologic Horizon W DXA scanner, and the Stratec peripheral quantitative computed tomography (pQCT) scanner.

Aim 1: To assess standard deviation (SD) and coefficient of variation (CV) of testing bone mineral, bone geometry, and soft tissues in inanimate objects and adults. Tests on adults will be structured to assess:

  • Within- and between-day variability of testing
  • Within- and between-technician variability of testing
  • Variability due to positioning and post-scan processing
  • Variability due to different DXA scanning equipment

Aim 2: To assess the least significant change (LSC) for testing bone mineral and soft tissues in adults.

Aim 3: To assess strengths and limitations of DXA and pQCT testing, including sensitivity to movement, rate of re-rescanning, etc. which are crucial components for demonstrating feasibility in grant applications.

Aim 4: To construct a database of DXA and pQCT test results and quality control procedures, showing our laboratory's quality control level.

Being studied: DXA and pQCT precision testing

Conditions: Bone and Bones; Body Composition

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

Healthy adults of two age groups, 1) aged 18-40 or 2) aged >40yr.

Exclusion Criteria

  • for females, being pregnant
  • Having had X-ray procedures using contrast material in the previous 3 days
  • Having medical devices that interfere with scan accuracy
  • Wearing external metal objects that cannot be removed
  • Having internal metal objects
  • Body mass of > 450 lbs.
  • Having ostomies

Recruiting US locations

  • Women's Health and Exercise Laboratories, The Pennsylvania State University

    University Park, PA 16802

    Site contact: Mary Jane De Souza, PhD · 814-863-0045 · mjd34@psu.edu

Study contacts (from the official record)

  • Mary Jane De Souza, PhD · 814-863-0045 · mjd34@psu.edu
  • Nicole Strock, MS · 814-863-4488 · nca11@psu.edu
DXA Study of Precision and Reliability (NCT03621306) | Bored Studies