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Effects of Daily Beef Intake, as a Component of a Heart-Healthy Diet on Cellular Zinc

University of California, Davis · with National Cattlemen's Beef Association, a contractor to the Beef Checkoff · NCT05236374

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 55–70 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
20
US sites recruiting
1
Study start
October 1, 2022
Record last updated
February 9, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The objective of the current study is to test the overarching hypothesis that the beef nutritive matrix is uniquely suited to direct dietary zinc to cellular compartments for improved metabolic function, leading to a greater effect on health outcomes. Specifically, whether beef, as a component of a healthy meal, will promote the absorption of zinc into cells, where the zinc will have greater effects on zinc-dependent metabolic processes supporting cardiovascular health. To maximize the observability of these beef-related effects, individuals who are 55- to 70-year-old who generally have a higher risk of zinc deficiency and cardiovascular disease will be enrolled.

Being studied: Beef protein

Conditions: Zinc Deficiency; Inflammation; Metabolic Diseases; Vascular Diseases

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Male or postmenopausal female 55-70 years of age
  • Women: lack of menses for at least two years.
  • Subject is willing and able to comply with the study protocols.
  • Subject is willing to participate in all study procedures
  • Self-reported stable dose of prescribed medications for a minimum of 6 months
  • BMI 18.5 - 29.9 kg/m2

Exclusion Criteria

  • Self-reported use of daily anticoagulation agents including aspirin, NSAIDs
  • Prescribed metaformin, statins or medications known to interfere with zinc, protein, or lipid metabolism
  • Vegan, Vegetarians, food faddists or those consuming a non-traditional diet (e.g. Adkins, Keto, Paleo, etc.)
  • Fruit consumption ≥ 3 cups/day
  • Regular consumption of strawberries (2-3 servings/week)
  • Vegetable consumption ≥ 4 cups/day
  • Coffee/tea ≥ 3 cups/day
  • Dark chocolate ≥ 3 oz/day
  • Alcohol intake greater than 2 drinks in a day for men, or 1 drink in a day for women.
  • Self-reported restriction of physical activity due to a chronic health condition
  • Self-reported chronic/routine high intensity exercise
  • Self-reported diabetes
  • Blood pressure ≥ 140/90 mm Hg
  • Self-reported renal or liver disease
  • Self-reported heart disease, which includes cardiovascular events and stroke
  • Peripheral artery disease Raynaud's syndrome or disease
  • Inability to properly place or wear the PAT probes or abnormal measurements on pre-screening PAT
  • Self-reported cancer within past 5 years
  • Self-reported malabsorption
  • Unwillingness to stop any supplement use six weeks prior to study initiation, including multivitamin/mineral, powders, herbal, plant or botanical, pro- and prebiotics, and oil supplements.
  • Smoking, vaping, cannabis use
  • Current enrollee in a clinical research study.

Recruiting US locations

  • University of California, Davis; Department of Nutrition

    Davis, CA 95616

    Site contact: Roberta Holt, PhD · 530-752-4950 · rrholt@ucdavis.edu

Study contacts (from the official record)

  • Roberta R Holt, PhD · 15304005952 · rrholt@ucdavis.edu
  • Andrew Hall, PhD · aghall@ucdavis.edu
All heart & blood pressure studies in California →
Effects of Daily Beef Intake, as a Component of a Heart-Healthy… (NCT05236374) | Bored Studies