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Effects of Mouthrinse on the Microbiome of the Oral Cavity and GI Tract

University of California, Irvine · NCT05603650

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18+ · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
200
US sites recruiting
1
Study start
September 1, 2021
Record last updated
December 17, 2025

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The purpose of this research study is to identify the effects of 2 over-the-counter mouthwashes on bacteria and 3 viruses in the participant's mouth and gut. The participant will be randomly allocated to rinse their mouth twice daily either with Listerine mouthwash, Lumineux Oral Essentials mouthwash, or water. The overall duration of the study will be approximately 180 days and will include approximately 5 visits and 15-30 minutes for each visit with a total of approximately 2.5 hours of your time. Additionally, fecal matter will also be collected in some subjects using a commercial collection kit.

Being studied: Lumineux Oral Essentials rinse; Listerine rinse

Conditions: Oral Bacterial Infection; Oral Infection; Microbial Colonization; Viral Infection

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Eligible men and non-pregnant and non-lactating women of all races age 18-25.
  • Volunteers must consent to participate in all scheduled exam visits and procedures.
  • Volunteers must be available for follow up on the telephone.
  • Healthy gums or gums that bleed when you brush them.

Exclusion Criteria

  • Volunteers unable or unwilling to sign the informed consent form.
  • Less than 20 teeth (excluding third molars).
  • Individuals who have taken antibiotics in the previous 3 months.
  • Presence of any condition, abnormality, or situation at Baseline that in the opinion of the Principal Investigator may preclude the volunteer's ability to comply with study requirements, including completion of the study or the quality of the data.

Recruiting US locations

  • Beckman Laser Institute and Medical Clinic

    Irvine, CA 92612

    Site contact: Nicole Wakida, PhD · 949-824-4360 · nwakida@uci.edu

Study contacts (from the official record)

  • Nicole Wakida, PhD · 949-824-4360 · nwakida@uci.edu
All healthy volunteers studies in California →
Effects of Mouthrinse on the Microbiome of the Oral Cavity and GI… (NCT05603650) | Bored Studies