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Evaluation of Multi-Cancer Early Detection Testing in a High-Risk Military Population: The Sentinel Study

Dana-Farber Cancer Institute · with United States Department of Defense · NCT06523868

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 45+ · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
1500
US sites recruiting
1
Study start
March 31, 2025
Record last updated
February 27, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The purpose of this research study is to evaluate the possible benefits of an investigational, but commercially available Galleri multi-cancer early detection (MCED) blood test which is designed to detect many types of cancer early in veterans who have served in the military in active duty.

The name of the screening blood test being studied is:

-GRAIL Galleri MCED test

Being studied: GRAIL Galleri

Conditions: Cancer Diagnosis

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Active-duty or National Guard/Reserves military service for four or more years
  • Age ≥ 45
  • Received care at a VA facility within past 5 years
  • Able to sign informed consent
  • Willingness to travel to Dana-Farber Cancer Institute in Boston, MA, for diagnostic testing if screening test indicates possible malignancy

Exclusion Criteria

  • Individuals diagnosed with invasive malignancy within 3 years of enrollment (non- melanoma skin cancer is acceptable)
  • Individuals with evidence of symptomatic or active cancer requiring therapeutic intervention at the time of participation (hormone therapy for breast/prostate cancer is acceptable)
  • Individuals in the process of being evaluated for a clinical suspicion of cancer

Recruiting US locations

  • Dana-Farber Cancer Institute

    Boston, MA 02215

    Site contact: Elizabeth O'Donnell, MD · 857-215-2361 · elizabeth_odonnell@dfci.harvard.edu

Study contacts (from the official record)

  • Elizabeth ODonnell, MD · 857-215-2361 · elizabeth_odonnell@dfci.harvard.edu
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Evaluation of Multi-Cancer Early Detection Testing in a High-Risk… (NCT06523868) | Bored Studies