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Exercise Effects on the Neurobiology Underlying Stress-related Eating Behaviors in Veterans

VA Office of Research and Development · NCT06627569

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–75 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
132
US sites recruiting
1
Study start
September 15, 2026
Record last updated
October 5, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The purpose of this study is to learn more about how common lifestyle interventions, such as exercise, affect how our brains respond to performing thinking tasks and to viewing pictures of foods and various other objects. The investigators are also interested in how changes in hormones that might be different in men and women could affect how lifestyle interventions change these brain responses.

Being studied: Exercise

Conditions: Overweight/Obesity; Stress

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Veteran
  • Body mass index (BMI) of 25 or greater
  • Physically inactive
  • Able to attend study visits in person in Aurora, CO

Exclusion Criteria

  • Currently pregnant
  • History of bariatric surgery
  • Current eating disorder
  • Current treatment with appetite-altering medications (e.g., glucagon-like peptide-1 (GLP-1) agonists)
  • Contraindication to MRI (weight > 500 pounds (lbs); claustrophobia; metal or electronic devices in the body)
  • Cardiovascular disease, chronic kidney disease, pulmonary disease, or diabetes
  • Unable to exercise due to cardiac, pulmonary, neurologic, or orthopedic reasons

Recruiting US locations

  • Rocky Mountain Regional VA Medical Center, Aurora, CO

    Aurora, CO 80045-7211

    Site contact: Kristina T Legget, PhD · (720) 724-5809 · kristina.legget@va.gov

Study contacts (from the official record)

  • Kristina T Legget, PhD · (720) 724-5809 · kristina.legget@va.gov
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Exercise Effects on the Neurobiology Underlying Stress-related… (NCT06627569) | Bored Studies