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RecruitingPhase 3

A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes

Eli Lilly and Company · NCT07282600

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18+ · All sexes
Healthy volunteers
Not accepted (a condition is required)
Study type
Interventional · Phase 3
Target enrollment
1035
US sites recruiting
60
Study start
December 15, 2025
Record last updated
October 8, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The main purpose of this study is to evaluate the efficacy and safety of eloralintide compared with placebo for body weight reduction in participants with overweight or obesity and type 2 diabetes. Participation in the study will last about 75 weeks.

Being studied: Eloralintide; Placebo

Conditions: Overweight; Obesity

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Have type 2 diabetes
  • Are on stable treatment for type 2 diabetes for at least 90 days prior to screening
  • Have a BMI ≥ 27 kg/m2
  • Have a stable body weight (\<5% body weight change) for 90 days prior to screening

Exclusion Criteria

  • Have a prior or planned surgical treatment for obesity (liposuction, cryolipolysis, or abdominoplasty allowed if performed >1 year before screening)
  • Have a prior or planned endoscopic procedure and/or device-based therapy for obesity (prior device-based therapy acceptable if device removal was more than 6 months prior to screening)
  • Have type 1 diabetes
  • Have taken any of the following antihyperglycemic medications within 90 days before screening:
  • amylin analogs
  • glucagon-like peptide-1 (GLP-1) receptor agonists
  • glucose-dependent insulinotropic polypeptide/glucagon-like peptide-1 (GIP/GLP) receptor agonists, or
  • insulin
  • Have had within 90 days prior to screening:
  • heart attack
  • stroke
  • coronary artery revascularization
  • unstable angina, or
  • hospitalization due to congestive heart failure
  • Have a history or diagnosis of New York Heart Association Functional Classification Class IV congestive heart failure
  • Have taken medications or alternative remedies intended for weight loss within 90 days of screening

Recruiting US locations

  • Birmingham Clinical Research

    Birmingham, AL 35209

    Site contact: 205-870-4343

  • Cullman Clinical Trials

    Cullman, AL 35055

    Site contact: 256-708-2826

  • Tucson Clinical Research Institute

    Tucson, AZ 85712

    Site contact: Girish Karamchandani

  • San Fernando Valley Health Institute

    Canoga Park, CA 91304

    Site contact: 818-222-6868

  • AMCR Institute

    Escondido, CA 92025

    Site contact: 760-466-1520

  • NorCal Medical Research, Inc

    Greenbrae, CA 94904

    Site contact: 415-461-1585

  • Ark Clinical Research

    Long Beach, CA 90815

    Site contact: Martha Navarro

  • Pacific Clinical Studies

    Los Alamitos, CA 90720

    Site contact: 562-598-0600 ext 205

  • Inglewood Clinical

    Los Angeles, CA 90056

    Site contact: 310-693-5000

  • Care Access - Santa Clarita

    Santa Clarita, CA 91321

    Site contact: 661-371-7272

  • Encompass Clinical Research

    Spring Valley, CA 91978

    Site contact: 619-660-9068

  • Diablo Clinical Research, Inc.

    Walnut Creek, CA 94598

    Site contact: 925-930-7267

  • Care Access - Aurora

    Aurora, CO 80012

    Site contact: 720-368-4865

  • New England Research Associates, LLC

    Bridgeport, CT 06606

    Site contact: 203-374-9816

  • CMR of Greater New Haven, LLC

    Hamden, CT 06517

    Site contact: Jillian Reid

  • Arrow Clinical Trials

    Daytona Beach, FL 32117

    Site contact: 386-278-8000

  • Care Access - Delray Beach

    Delray Beach, FL 33484

    Site contact: 401-773-7855

  • Fleming Island Center for Clinical Research

    Fleming Island, FL 32003

    Site contact: 904-621-0390

  • Nature Coast Clinical Research - Inverness

    Inverness, FL 34452

    Site contact: 352-341-2100

  • Jacksonville Center for Clinical Research

    Jacksonville, FL 32216

    Site contact: 904-730-0101

  • Flourish Research Acquisition, LLC dba Flourish Research - North Miami

    Miami, FL 33138

    Site contact: 786-772-0411

  • New Horizon Research Center

    Miami, FL 33165

    Site contact: 305-226-3933

  • Adult Medicine of Lake County, Inc.

    Mt. Dora, FL 32757

    Site contact: 352-383-8222

  • American Research Centers of Florida

    Pembroke Pines, FL 33027

    Site contact: 954-237-3799

  • Clinical Site Partners, LLC dba Flourish Research

    Winter Park, FL 32789

    Site contact: 407-740-8078

  • Teak Research Consults - Dunwoody

    Dunwoody, GA 30338

    Site contact: 470-403-4755

  • Teak Research Consults

    Lawrenceville, GA 30043

    Site contact: Kamar Alabi

  • The Jones Center Clinical Research

    Macon, GA 31210

    Site contact: Susan Garcia Castillo

  • Pacific Diabetes & Endocrine Center

    Honolulu, HI 96817

    Site contact: 808-526-0303

  • NorthShore University Health System

    Skokie, IL 60077

    Site contact: 847-663-8540

  • DM Clinical Research - Indianapolis

    Indianapolis, IN 46254

    Site contact: 463-271-3050

  • Clinical Trials Management, LLC d/b/a Flourish Research

    Metairie, LA 70006

    Site contact: 504-455-1310

  • IMA Clinical Research Monroe - Armand

    Monroe, LA 71201

    Site contact: Clinton Guillory

  • Centennial Medical Group

    Columbia, MD 21045

    Site contact: 410-730-3399

  • Lucida Clinical Trials

    New Bedford, MA 02740

    Site contact: 508-720-2015

  • Clinical Research Professionals

    Chesterfield, MO 63005

    Site contact: 636-220-1200

  • Clinvest Headlands Llc

    Springfield, MO 65807

    Site contact: 417-883-7889

  • Hypertension & Nephrology Association

    Eatontown, NJ 07724

    Site contact: spiros Arbes

  • IMA Clinical Research Warren

    Warren Township, NJ 07059

    Site contact: Nancy Phillips

  • Albuquerque Clinical Trials, Inc.

    Albuquerque, NM 87102

    Site contact: 505-224-7407

  • NYC Research INC

    Long Island City, NY 11106

    Site contact: 516-574-9232

  • PharmQuest Life Sciences, LLC

    Greensboro, NC 27408

    Site contact: 336-574-8020

  • West Clinical Research

    Morehead City, NC 28557

    Site contact: 252-515-0050

  • Trial Management Associates - Wilmington - Floral Parkway

    Wilmington, NC 28403

    Site contact: William Jones

  • Lillestol Research

    Fargo, ND 58104

    Site contact: 701-232-7705

  • Care Access - Lima

    Lima, OH 45805

    Site contact: Jimmy Alele

  • Summit Headlands

    Portland, OR 97210

    Site contact: Andre Barkhuizen

  • Preferred Primary Care Physicians, Preferred Clinical Research-St. Clair

    Pittsburgh, PA 15243

    Site contact: 412-942-0023

  • Preferred Primary Care Physicians

    Uniontown, PA 15401

    Site contact: 724-438-1479

  • Accellacare - Mt Pleasant

    Mt. Pleasant, SC 29464

    Site contact: 843-849-1880

  • IMA Clinical Research Austin

    Austin, TX 78745

    Site contact: Yu-Mei Liu

  • Private Practice - Dr. Osvaldo A. Brusco

    Corpus Christi, TX 78414

    Site contact: 361-885-0448

  • Velocity Clinical Research, Dallas

    Dallas, TX 75230

    Site contact: Dan Lender

  • Diabetes and Thyroid Center of Ft. Worth

    Fort Worth, TX 76132

    Site contact: 817-263-0007

  • Juno Research

    Houston, TX 77040

    Site contact: 713-779-5494

  • Southern Endocrinology Associates

    Mesquite, TX 75149

    Site contact: 214-693-0904

  • Research Your Health

    Plano, TX 75093

    Site contact: 9729991155 x103

  • IMA Clinical Research San Antonio

    San Antonio, TX 78229

    Site contact: 210-692-7157

  • Ogden Clinic - Canyon View

    Ogden, UT 84404

    Site contact: 385-271-0684

  • Diabetes & Endocrine Treatment Specialists

    Sandy City, UT 84093

    Site contact: 801-816-1010

Study contacts (from the official record)

  • Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or · 317-615-4559 · LillyTrials@Lilly.com
  • Physicians interested in becoming principal investigators please contact · clinical_inquiry_hub@lilly.com
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A Study of Eloralintide (LY3841136) in Participants With Obesity… (NCT07282600) | Bored Studies