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EyeConic: Qualification for Cone-Optogenetics

Institute of Molecular and Clinical Ophthalmology Basel · NCT05294978

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Any age listed · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
1000
US sites recruiting
3
Study start
July 1, 2021
Record last updated
July 31, 2025

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

This study aims to prepare for the first-in-human clinical trial of cone optogenetics vision restoration. As a first step, this worldwide multicenter ocular imaging study (EyeConic Study) is performed to identify eligible patients.

Being studied: Optical coherence tomography (OCT)

Conditions: Retinal Dystrophies

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria (patients):

  • Diagnosis of generalized IRD
  • Low vision as defined as visual acuity worse or equal to 0.05 (or 20/400) in the study eye
  • Availability of macular optical coherence tomography (OCT)

Inclusion Criteria (controls):

  • Normal ophthalmic findings
  • Availability of macular optical coherence tomography (OCT)

Exclusion Criteria (all):

  • Other eye diseases with a significant effect on vision or retinal structure
  • Extraocular disease affecting retinal structure such as neurodegenerative diseases

Recruiting US locations

  • University of California San Francisco, Department of Ophthalmology

    San Francisco, CA 94158

    Site contact: Jacque Duncan, MD

  • Bascom Palmer Eye Institute

    Miami, FL 33136

    Site contact: Byron L Lam, MD

  • University of Pittsburgh, Department of Ophthalmology

    Pittsburgh, PA 15213

    Site contact: Jose A Sahel, MD

Study contacts (from the official record)

  • Lucas Janeschitz-Kriegl, MD · +41787494373 · lucas.janeschitz@iob.ch
  • Tiana Koottungal · +41788486737 · tiana.koottungal@iob.ch
EyeConic: Qualification for Cone-Optogenetics (NCT05294978) | Bored Studies