FIT Exercise in 30d of ULLS-induced Muscle Disuse
Lance Bollinger · with University of Louisville, National Aeronautics and Space Administration (NASA) · NCT06631053
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 35–45 · All sexes
- Healthy volunteers
- Accepted
- Study type
- Interventional · Not applicable
- Target enrollment
- 16
- US sites recruiting
- 1
- Study start
- October 23, 2024
- Record last updated
- October 24, 2025
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
This study aims to determine how flywheel-based inertial training (FIT) implemented according to principles of velocity-based training (VBT) and High-Intensity Interval Training (HIIT) affects disuse-induced physical de-conditioning including loss of voluntary muscle strength, aerobic capacity, and balance regulation.
Being studied: velocity-based FIT (VBFIT); No Exercise
Conditions: Muscle Atrophy; Muscle Weakness
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Inclusion Criteria
- Regularly engaging in aerobic exercise (> 150min/wk) and resistance exercise (>1 time per week) for the past 12 months
- Education greater than or equal to bachelor's degree (any field)
Exclusion Criteria
- Waist circumference \< 55cm or > 90cm (F) and \< 75cm or > 100cm (M)
- Body mass index \< 18.5 or > 29.9
- Shoe size \< 25 or >29cm.
- Not regularly engaging in exercise for previous 12 months
- Tobacco use within previous 6 months
- Blood clotting disorder
- Heart arrhythmia
- Implanted device which could negatively be affected by electrical impulse or strong magnetic field such as pacemaker, internal defibrillator, or cochlear implant
- Diagnosed cardiovascular, pulmonary, renal, or metabolic disease
- Pregnancy (within previous 6 months)
- Oral contraceptive use (within previous three months)
- High resting blood pressure (>140 systolic and/or > 90 diastolic)
- Currently or previously undergone gender-affirming therapy (hormone therapy or sexual reassignment surgery)
- Low back or leg injury in previous 6 months
- Currently taking medication to assist with sleep
- Muscle, bone, or joint injury that limits physical activity within previous 6 months
- Neurological disorder which affects balance (such as multiple sclerosis or Parkinson's disease)
Recruiting US locations
University of Kentucky
Lexington, KY 40506
Study contacts (from the official record)
- Lance Bollinger, PhD · 8592577904 · lance.bollinger@uky.edu
Similar studies in Kentucky
All healthy volunteers studies in Kentucky →- RecruitingHealthy volunteersPhase 1
A Clinical Study of Novel Pneumococcal Vaccine V118C in Children (V118C-002)
Merck Sharp & Dohme LLC
- Location
- Louisville, KY + 14 other US sites
- Eligibility basics
- Ages 2 mo–1
- RecruitingHealthy volunteersPhase 1/Phase 2
Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis
Xencor, Inc.
- Location
- Louisville, KY + 27 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteersPhase 1/Phase 2
Study of GS-4321 in Healthy Participants and Participants With Chronic Hepatitis Delta Virus
Gilead Sciences
- Location
- Louisville, KY + 4 other US sites
- Eligibility basics
- Ages 18–69
- RecruitingHealthy volunteersPhase 1/Phase 2
A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
Novartis Pharmaceuticals
- Location
- Louisville, KY + 18 other US sites
- Eligibility basics
- Ages 18–100