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Food and Circadian Timing

Oregon Health and Science University · with National Institutes of Health (NIH) · NCT04743271

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–40 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
14
US sites recruiting
1
Study start
April 1, 2022
Record last updated
October 16, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The goals of this study are to uncover the influence of diet on the human circadian timing system. The protocol is a 46-day (28 outpatient days, 18 inpatient days over two 9 day visits) randomized cross-over study designed to elucidate the speed of entrainment in response to a high-fat diet.

Being studied: High-Fat Diet; Low-Fat Diet

Conditions: Diet, High-Fat; Circadian Rhythm

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Healthy, lean men and women

Exclusion Criteria

  • Major dietary restrictions (such as entirely dairy-free and/or meat-free diets)
  • A body mass index (BMI) of 18.5\< [BMI] \< 24.9 kg/m\^2 and a waist circumference \<94/80cm
  • Currently psychiatrically/psychologically unsuitable for participation
  • Drug/alcohol use, including smoking
  • Medication/drug use, including prescribed and over-the-counter medications
  • History of working irregular day and night hours, regular night work, or rotating shift work for the 1 year prior to the study.
  • Traveled across more than 1 time zone during the 3 months prior to the study
  • Currently consuming a habitual high-fat diet
  • Chronobiologic and sleep disorders
  • Diseases of the Cardiovascular System
  • Metabolic Syndrome; Two or more of these factors will be excluded from the study:
  • HDL cholesterol of less than 40 mg/dL in men or less than 50 mg/dL in women;
  • systolic blood pressure>135 mmHg or diastolic blood pressure>85 mmHg;
  • Fasting blood glucose ≥ 100 mg/dL;
  • Triglycerides ≥ 150 mg/dL.
  • Pre-Diabetes/Diabetes
  • Hypertension
  • Disorders of the Respiratory System
  • Disorders of the Kidney and Urinary Tract
  • Infectious Diseases
  • Disorders of the Gastrointestinal System
  • Disorders of the Immune System
  • Disorders of the Hematopoietic System
  • Neoplastic Diseases
  • Endocrine and Metabolic Diseases
  • Neurologic Disorders
  • Subjects must not be currently participating in another research study that would influence their safe participation in our study

Recruiting US locations

  • Oregon Health & Science University

    Portland, OR 97239

    Site contact: Andrew W McHill, PhD · 5034942594 · mchill@ohsu.edu

Study contacts (from the official record)

  • Andrew McHill, PhD · 503-494-2594 · mchill@ohsu.edu
All sleep studies in Oregon →
Food and Circadian Timing (NCT04743271) | Bored Studies