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Fully Automated High-Throughput Quantitative MRI of the Liver

University of Wisconsin, Madison · with National Institute for Biomedical Imaging and Bioengineering (NIBIB) · NCT05294471

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 7+ · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
204
US sites recruiting
1
Study start
October 16, 2023
Record last updated
September 16, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The purpose of this research is to see if a new automated magnetic resonance imaging (MRI) method will be able to improve the images taken of the liver. Participants will have either known or suspected liver disease, known or suspected iron overload syndrome, or be a healthy adult. Participants will be in the research study for one day.

Being studied: Non-contrast MRI with novel MRI software

Conditions: Healthy; Iron Overload; Liver Fat

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Eligibility Criteria for Substudies 1, 2, 4, 5

Inclusion Criteria

  • Age 18 years or older

Exclusion Criteria

  • Patients with contraindication to MRI (e.g. pacemaker, contraindicated metallic implants, claustrophobia, etc)
  • Pregnant or trying to become pregnant (as determined by self-report during MRI safety screening)

Eligibility Criteria for Substudy 3

Inclusion Criteria

  • Age 7 years or older
  • One of:
  • Known or suspected liver iron overload
  • Known or suspected elevated liver fat

Exclusion Criteria

  • Patients with contraindication to MRI (e.g. pacemaker, contraindicated metallic implants, claustrophobia, etc)
  • Patients requiring intravenous (IV) conscious sedation for imaging are not eligible; patients requiring mild, oral anxiolytics for the MRI will be allowed to participate as long as the following criteria are met:
  • The subject has their own prescription for the medication.
  • The informed consent process is conducted prior to the self-administration of this medication
  • They come to the research visit with a driver
  • Pregnant or trying to become pregnant (as determined by self-report during MRI safety screening)

Eligibility Criteria for Substudy 6

Inclusion Criteria

  • Age 7 years or older
  • Scheduled for a clinical abdominal MRI exam

Exclusion Criteria

  • Patients with contraindication to MRI (e.g. pacemaker, contraindicated metallic implants, claustrophobia, etc)
  • Sedation required for MRI
  • Pregnant or trying to become pregnant (as determined by self-report during MRI safety screening)

Recruiting US locations

  • University of Wisconsin

    Madison, WI 53705

    Site contact: Scott Reeder, MD, PhD

Study contacts (from the official record)

  • Radiology Studies · 608-282-8349 · radstudy@uwhealth.org
All nutrition & metabolism studies in Wisconsin →
Fully Automated High-Throughput Quantitative MRI of the Liver (NCT05294471) | Bored Studies