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Functional Evaluation in Patients With Urea Cycle Disorders (UCD) During a Driving Task

St. Jude Children's Research Hospital · NCT07701694

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 16–40 · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
60
US sites recruiting
1
Study start
July 20, 2026
Record last updated
July 31, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

This study is being done to understand how the brain works while people with urea cycle disorder (UCD) perform driving tasks that range from easy to difficult and to look at how that compares to traditional tests of thinking and attention.

Conditions: Urea Cycle Disorder

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Individuals 16 to 40 years with molecular or biochemical confirmation of a urea cycle disorder.
  • Healthy individuals will serve as an age and sex matched comparison group. Active driver's license for at least 6 months
  • Read and understand English. as the tasks have not been validated in other languages
  • IQ >=70.

Exclusion Criteria

  • Skin disease that affects the scalp
  • Past or present vascular disease
  • Head trauma with loss of consciousness in the last year or evidence of cognitive impairment due to and persisting after head trauma
  • Motor movement disorder which may cause excessive movement or impede use of the steering wheel and/or pedal
  • Premature birth or birth before 32 weeks of gestation
  • The participant is taking a stimulant or antidepressant
  • Allergy to any component of the device, although expected to be rare
  • History of psychosis
  • Self-reported motion or cyber sickness
  • Self-reported illicit substance use
  • Vision disorder

Recruiting US locations

  • St. Jude Children's Research Hospital

    Memphis, TN 38105

    Site contact: Jean Laboe, RN · 901-595-1693 · jean.laboe@stjude.org

Study contacts (from the official record)

  • Jean Laboe, RN · 901-595-1693 · jean.laboe@stjude.org
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Functional Evaluation in Patients With Urea Cycle Disorders (UCD)… (NCT07701694) | Bored Studies