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Genomic Risk in Retroperitoneal Sarcoma

Fox Chase Cancer Center · NCT06436846

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18+ · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
50
US sites recruiting
1
Study start
March 7, 2022
Record last updated
May 31, 2024

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The protocol intends to explore the biology which may underlie recurrences of retroperitoneal liposarcoma. Surgery remains the only curative intent intervention for this disease. Often, tumors recur in locations within the retroperitoneum remote from the original primary tumor. This study hypothesizes that normal appearing retroperitoneal fat actually harbors underlying genetic changes which predispose to development of future liposarcoma. To accomplish this goal, retroperitoneal fat is sampled from quadrants within and remote from the primary tumor and is subsequently subjected to genetic analyses looking for such predisposing factors.

Being studied: Biospecimen sample collection during standard-of-care surgery

Conditions: Retroperitoneal Liposarcoma; Soft Tissue Sarcoma

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Adult patients (age ≥18 years).
  • Histologically confirmed retroperitoneal liposarcoma via preoperative biopsy, or cross-sectional imaging suspicious for liposarcoma with planned surgical resection
  • Will be undergoing surgical resection for treatment of primary or recurrent disease
  • Have provided informed consent to participate in this study

Exclusion Criteria

  • Prior surgical anatomy which makes sampling of remote areas of the retroperitoneum technically impossible or clinically undesirable for safety reasons

Recruiting US locations

  • Fox Chase Cancer Center

    Philadelphia, PA 19111

    Site contact: Anthony Villano, MD · 215-728-3686 · anthony.villano@fccc.edu

Study contacts (from the official record)

  • Anthony Villano, MD · 215-728-3686 · anthony.villano@fccc.edu
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Genomic Risk in Retroperitoneal Sarcoma (NCT06436846) | Bored Studies