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Glaucoma, Visual Field Loss, and Their Association With Life Space in Older Adults

University of Alabama at Birmingham · NCT04396002

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–100 · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
100
US sites recruiting
1
Study start
June 1, 2019
Record last updated
September 12, 2025

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

Mobility refers to a person's purposeful movement through the environment from one place to another and can be conceptualized as a continuum from bed bound (immobility) on one extreme to making excursions to distant locations on the other extreme. Primary open-angle glaucoma (POAG) is a chronic, progressive optic neuropathy that can lead to gradual loss of vision in the peripheral field and central vision. Older adults with POAG have an increased risk for motor vehicle collisions and falls. Moreover, existing studies suggest that patients with POAG exhibit more postural sway while standing as measured by a balance platform and also tend to walk more slowly than those who are normally sighted and free of ocular disease. While these disturbances likely influence mobility, there has been little research directly assessing the impact of POAG on mobility. This study will assess the impact of POAG on life space (one aspect of mobility) and will determine whether difficulties with life space are associated with difficulties experienced under conditions of dim lighting.

Being studied: Life Space Questionnaire; Low Luminance Questionnaire; Contrast sensitivity under dim illumination; Visual field under dim illumination (MAIA); Macular Pigment Optical Density (MPOD); Dark Adaptation

Conditions: Primary Open Angle Glaucoma

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria (Patients):

  • Participants that are enrolled in the Early Detection of Glaucoma Progression using a Novel Individualized Approach (IRB-300000301) or in the African Descent and Glaucoma Evaluation (ADAGES) IV: Alterations of the Lamina Cribrosa in Progression (IRB-161115004).

Exclusion Criteria (Patients):

  • Not being enrolled in one of the following two NIH-funded studies: 1. African Descent and Glaucoma Evaluation (ADAGES) IV: Alterations of the lamina cribrosa in progression (EY026574) or 2. Early detection of glaucoma progression using a novel individualized approach (EY025756)

Inclusion Criteria (Controls):

  • No diagnosis of eye disease

Exclusion Criteria (Controls):

  • Cognitive impairment that would preclude ability to take the tests

Recruiting US locations

  • University of Alabama Birmingham

    Birmingham, AL 35294-0001

    Site contact: Lyne Racette, PhD · 2053258673 · lracette@uabmc.edu

Study contacts (from the official record)

  • Lyne Racette, PhD · 205-325-8673 · lracette@uabmc.edu
All healthy volunteers studies in Alabama →
Glaucoma, Visual Field Loss, and Their Association With Life Space… (NCT04396002) | Bored Studies