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Hormonal, Metabolic, and Signaling Interactions in PAH

Vanderbilt University Medical Center · NCT01884051

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Up to age 90 · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
1899
US sites recruiting
1
Study start
September 2012
Record last updated
September 25, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

Our hypothesis is that optimal treatment of the dysfunctional metabolic pathways which underlie PAH will improve pulmonary vascular function and consequences of the disease.

Conditions: Idiopathic Pulmonary Arterial Hypertension; Heritable Pulmonary Arterial Hypertension; Scleroderma Associated Pulmonary Arterial Hypertension; Appetite Suppressant Associate PAH

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

Project 1

Inclusion

  • Diagnosis of IPAH (idiopathic pulmonary arterial hypertension), HPAH (heritable pulmonary arterial hypertension), or APAH (associated pulmonary arterial hypertension), family members of affected persons
  • Age 0-90, age 12-90 for skin biopsy

Exclusion

  • Other diagnosis
  • Age greater than 90, age less than 12 or greater than 90 for skin biopsy

Project 2

Inclusion

  • Diagnosis of IPAH, HPAH, or APAH, family members of affected persons
  • 0-90
  • Subjects with reasonably easy access to clinic for blood collection and other testing
  • Subject able to tolerate fasting state prior to sample collection and EndoPAT (endothelial function assessment) testing

Exclusion

  • Other diagnosis
  • 0-90
  • Subjects with difficulty reaching clinic for blood collection and other testing
  • Subjects unable to tolerate fasting state

Project 3

Inclusion

  • Diagnosis of IPAH, HPAH, or APAH, family members of affected persons
  • 7-90

Exclusion

  • Other diagnosis
  • Age less than 7 or greater than 90

-

Exclusion Criteria

-

Recruiting US locations

Study contacts (from the official record)

  • Kelly L Fox · 800-288-0378 · Kelly.Burke@vumc.org
  • Shannon Cordell, BSN · 615-343-8277 · shannon.eason@vumc.org
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Hormonal, Metabolic, and Signaling Interactions in PAH (NCT01884051) | Bored Studies