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Hot Flashes and Neurovascular Function in Women

Mayo Clinic · with National Institutes of Health (NIH), National Heart, Lung, and Blood Institute (NHLBI) · NCT05193968

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 40–60 · Women only
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
120
US sites recruiting
1
Study start
February 24, 2022
Record last updated
June 12, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

Women who experience hot flashes are at greater risk for hypertension and other cardiovascular disease. Neurovascular control mechanisms are likely to play an important role in this relationship. As such, these studies are designed to provide a major step forward in understanding the link between hot flashes and neurovascular dysfunction and, by extension, cardiovascular disease in women.

Being studied: Sympathoexcitatory stressors; Sodium Nitroprusside; Acetylcholine; Terbutaline; Norepinephrine

Conditions: Hot Flashes; Menopause; Vasomotor System; Labile

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Non-smokers.
  • Non-obese.
  • Have at least one ovary.
  • Free from cardiovascular disease.
  • Not taking medications influencing cardiovascular function.

Exclusion Criteria

  • None.

Recruiting US locations

  • Mayo Clinic in Rochester

    Rochester, MN 55905

    Site contact: Pamela A Engrav · 507-255-6938

Study contacts (from the official record)

  • Pamela A Engrav · 507-255-6938 · engrav.pamela@mayo.edu
  • Nancy J Meyer · 507-255-0913 · meyer.nancy2@mayo.edu
All women’s health studies in Minnesota →
Hot Flashes and Neurovascular Function in Women (NCT05193968) | Bored Studies