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RecruitingAccepts healthy volunteersPhase 1

Hyperpolarized 129Xe MR Imaging of Lung Function in Healthy Volunteers and Subjects With Pulmonary Disease

Mario Castro, MD, MPH · NCT04624490

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 3+ · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Phase 1
Target enrollment
260
US sites recruiting
1
Study start
November 2, 2020
Record last updated
May 6, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The purpose of this study is to develop and evaluate the usefulness of hyperpolarized (HP) 129Xe gas MRI for regional assessment of pulmonary function.

Being studied: Hyperpolarized Xe129

Conditions: Asthma; COPD; Interstitial Lung Disease; Cystic Fibrosis; Pulmonary Hypertension; Pulmonary Infection; Other Lung Disease

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

Healthy Volunteers

  • Subject has no diagnosed pulmonary conditions
  • Ability to read and understand English or Spanish

Subjects with Lung Disease

  • Subject has a diagnosis of pulmonary dysfunction made by a physician
  • No acute worsening of pulmonary function in the past 30 days
  • Ability to read and understand English or Spanish

Exclusion Criteria

  • MRI is contraindicated based on responses to MRI screening questionnaire
  • Subject is pregnant or lactating
  • Subject does not fit into 129Xe vest coil used for MRI
  • Subject cannot hold his/her breath for 15-16 seconds
  • Subject deemed unlikely to be able to comply with instructions during imaging
  • Oxygen saturation \<88% on room air or with supplemental oxygen
  • Cognitive deficits that preclude ability to provide consent
  • Institutionalization

Recruiting US locations

  • University of Kansas Medical Center

    Kansas City, KS 66160

    Site contact: Peter J Niedbalski, PhD · 9135882271 · pniedbalski@kumc.edu

Study contacts (from the official record)

  • Cristal Monge · 913-945-9399 · chernandez@kumc.edu
All heart & blood pressure studies in Kansas →
Hyperpolarized 129Xe MR Imaging of Lung Function in Healthy… (NCT04624490) | Bored Studies