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Immune Status After Being on Call for 24 Hrs

University of Chicago · NCT06636318

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18+ · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
60
US sites recruiting
1
Study start
October 17, 2024
Record last updated
December 9, 2025

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

Sleep deprivation is a prevalent problem in modern societies. Sleep deprivation can cause hormonal changes, such as an increase in cortisol, as well as inflammation. Animal studies have shown an increase in inflammatory cytokine production following sleep deprivation. Additionally, humans experiencing sleep deprivation may experience a decrease in natural killer cells and lymphocytes.

Physicians, particularly those in surgical specialties, are often subjected to sleep deprivation as part of their medical residency training. This study hypothesizes that after 24-hour shifts, there is an increase in inflammatory response and impairment of the immune response against unspecific activation. This proposal aims to provide insight into the impact of sleep deprivation on the immune system of surgery residents by characterizing the phenotype and function of immune cells, as well as their correlation with biometric data.

Being studied: Blood Sample Collection; Actigraph (GT9X-BT) Monitor

Conditions: Sleep Deprivation

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Healthy subjects
  • Surgery residents in a 24-hour shift rotation
  • Gender of subjects: Males and females
  • Age of subjects: 18 years old and older
  • Racial and Ethnic Origin: Any race or ethnicity

Exclusion Criteria

  • Unwilling/unable to sign informed consent
  • Vulnerable Subjects/Subject Capacity to provide consent

Recruiting US locations

  • The University of Chicago

    Chicago, IL 60637

    Site contact: Shalitha Johnson · 773-834-8758 · sjohnson28@bsd.uchicago.edu

Study contacts (from the official record)

  • Angelica Perez-Gutierrez, MD · 773-834-5087 · rperezgutierrez@bsd.uchicago.edu
  • Leila Yazdanbakhsh · leila.yazdanbakhsh@bsd.uchicago.edu
All sleep studies in Illinois →
Immune Status After Being on Call for 24 Hrs (NCT06636318) | Bored Studies