Impact of Nd:YAG Laser Photobiostimulation on Healing of Gingiva
Medical University of South Carolina · NCT07095556
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 18+ · All sexes
- Healthy volunteers
- Accepted
- Study type
- Interventional · Not applicable
- Target enrollment
- 39
- US sites recruiting
- 1
- Study start
- November 5, 2025
- Record last updated
- November 12, 2025
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
The intervention in this study is to determine whether multiple applications of photobiostimulation with Nd-YAG laser improve wound healing following tooth extraction and alveolar ridge preservation. Investigators plan to assess the impact of laser treatment on wound healing by measuring salivary biomarkers, gingival wound size and surveying for the use of pain reduction and patient satisfaction. The intervention group will receive extraction and alveolar ridge preservation with Nd-YAG laser photobiostimulation on days 1, 3, and 7 following extraction and socket preservation, while the control group will receive the standard of care extraction and alveolar ridge preservation without the laser
Being studied: Low-level laser therapy
Conditions: Wound Healing and Prevention; Oral Inflammation; Photobiomodulation; Post-operative Pain Management; Tooth Extraction Site Healing
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Inclusion Criteria
- Participants who are ≥ 18 years old,
- Patients who are scheduled for the treatment of tooth extraction and alveolar ridge preservation (ARP)
- No contraindications for tooth extraction and alveolar ridge preservation based on electronic health records.
- Participants who can express the level of pain
- Participants who self-report "not pregnant"
Exclusion Criteria
- Untreated periodontal disease
- Acute infection of the teeth
- Use of antibiotics within the last three months.
- Pregnant or lactating women
- Use of bisphosphonates based on EHR
- Alveolar bone defects occurred or were detected during tooth extraction
Recruiting US locations
MUSC College of Dental Medicine, Graduate Periodontics Clinic
Charleston, SC 29425
Site contact: Joe Gambacorta, DDS · 843-876-7645 · gambacor@musc.edu
Study contacts (from the official record)
- Pinar Emecen-Huja · (843) 792-5688 · emecenh@musc.edu
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