Improving Speech in Noise Using Noninvasive Stimulation
University of Florida · with Congressionally Directed Medical Research Programs · NCT07176936
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 25–55 · All sexes
- Healthy volunteers
- Accepted
- Study type
- Interventional · Not applicable
- Target enrollment
- 55
- US sites recruiting
- 1
- Study start
- March 21, 2026
- Record last updated
- March 27, 2026
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
Traumatic brain injury, a common injury in military service personnel, often leads to poor processing of speech in noisy environments. The goal of the current study is to better understand the brain basis for this difficulty and evaluate a new approach to improving speech in noise perception.
Being studied: Cymba Conchae stimulation; Earlobe stimulation
Conditions: Traumatic Brain Injury; Hearing Loss
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Inclusion Criteria
- 25-55 years old
- Proficiency in English
- TBI group: history of traumatic brain injury by blast or physical trauma
- Normal hearing group: no history of traumatic brain injury
Exclusion Criteria
- Other neurological diseases or related conditions will be excluded (e.g., large vessel stroke, seizures). We will exclude patients with severe medical diseases that may be associated with impaired cognition (e.g., heart failure, dialysis dependent kidney disease, brain cancer). Further, psychiatric diseases that are unlikely to be related to trauma will be excluded (e.g., schizophrenia).
Patients with histories of severe psychiatric disease prior to trauma exposure will be excluded.
- Current illicit or prescription drug abuse (within the last two months)
- Any taVNS contraindication, including but not limited to the presence of unremovable metal in the left ear, known heart conditions, medications that influence neurotransmitters thought to be critical for vagus nerve stimulation (norepinephrine, acetylcholine, and serotonin), or implanted medical devices such as a pacemaker.
Recruiting US locations
UF Health at the University of Florida
Gainesville, FL 32610
Site contact: Tracy Centanni, Ph.D. · 352-294-8675 · tracy.centanni@phhp.ufl.edu
Similar studies in Florida
All neurology studies in Florida →- RecruitingHealthy volunteersPhase 1
A Study of LY4405094 in Healthy Participants and Participants With Alzheimer's Disease
Eli Lilly and Company
- Location
- Daytona Beach, FL
- Eligibility basics
- Ages 18–85
- RecruitingHealthy volunteersPhase 1
A Clinical Trial of LY3962681 in Healthy Volunteers and in Patients With Parkinson's Disease
Prevail Therapeutics
- Location
- Naples, FL + 1 other US site
- Eligibility basics
- Ages 30–80
- RecruitingHealthy volunteersPhase 1
A Study of LY4006896 in Healthy Participants and Participants With Parkinson's Disease
Eli Lilly and Company
- Location
- Naples, FL + 7 other US sites
- Eligibility basics
- Ages 30–85
- RecruitingHealthy volunteersPhase 1
A Master Protocol Studying Multiple Amyloid-Targeting Therapies in Healthy Participants and Participants With Alzheimer's Disease
Eli Lilly and Company
- Location
- Daytona Beach, FL
- Eligibility basics
- Ages 18–85