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RecruitingAccepts healthy volunteersEarly Phase 1

Impulsivity Domains and Subjective Response

Jessica Weafer · with National Institute on Alcohol Abuse and Alcoholism (NIAAA) · NCT05929677

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 21–25 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Early Phase 1
Target enrollment
250
US sites recruiting
2
Study start
April 1, 2024
Record last updated
May 22, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

Findings from this project will determine the relationship between two vulnerability factors for Alcohol Use Disorder (AUD) in young adults: impulsivity and subjective response to alcohol. The results will identify badly needed, novel targets for prevention and treatment efforts to simultaneously reduce impulsivity and subjective responses in at-risk young adults.

Being studied: Placebo; Alcohol

Conditions: Alcohol Use Disorder

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • 21-25 years old
  • Report drinking to an estimated BAC > .08% at least once in the past 30 days based on responses on the Timeline Followback (TLFB)
  • Report drinking at least twice weekly in the past 30 days based on responses on the TLFB
  • Fluency in English

Exclusion Criteria

  • Any serious medical problems (e.g., liver disease, cardiac abnormality, pancreatitis, diabetes, neurological problems, and gastrointestinal disorders)
  • Body weight \< 110 or > 210 pounds
  • Axis I psychiatric disorders including substance use disorder other than mild or moderate alcohol or mild cannabis use disorder
  • Current alcohol withdrawal or history of medically-assisted detoxification
  • Two positive breath alcohol concentration (BrAC) readings (i.e., > 0.00%) at an in-person screening appointment or experimental session
  • Positive urine screen for illegal drugs other than cannabis
  • Currently seeking or past-12-month history of inpatient or intensive treatment for addictive behaviors
  • Current psychotropic medication use or receipt of a prescription for these medications in the past 30 days
  • Psychosis or other psychiatric disability
  • Pregnancy, nursing or lack of reliable birth control use for women
  • Report smoking > 5 cigarettes per day (to avoid acute nicotine effects or withdrawal during experimental sessions)

Recruiting US locations

  • Northeastern University

    Boston, MA 02115

    Site contact: Robert Leeman · 617-373-6501 · r.leeman@northeastern.edu

  • Ohio State University

    Columbus, OH 43221

    Site contact: Jessica Weafer, PhD · 614-257-2075 · jessica.weafer@osumc.edu

Study contacts (from the official record)

  • Jessica Weafer, PhD · 614-257-2075 · jessica.weafer@osumc.edu
All healthy volunteers studies in Massachusetts →
Impulsivity Domains and Subjective Response (NCT05929677) | Bored Studies