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Increasing the Repertoire of Intermuscular Co-ordination Post Stroke Through EMG-Guided Human-Machine Interaction

University of Houston · with Korea Advanced Institute of Science and Technology, The University of Texas Health Science Center, Houston · NCT06523335

Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

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The purposes of this study include

- To identify whether features of aberrant intermuscular coordination patterns can be used to predict motor impairment after stroke.
- To test whether muscle synergies are malleable to a non-invasive EMG-guided exercise that induces changes in intermuscular coordination of upper extremity muscles after stroke.

Being studied: Neuromuscular coordination-guided rehabilitative training; Force strengthening-guided rehabilitative training

Conditions: Stroke

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion criteria for aged matched healthy group

Exclusion criteria for aged matched healthy group

have an orthopedic disorder involving upper limbs;
have a history of any neurologic disease;
have any history of epilepsy of the potential participants and/or their family members;
are unable to consent;
are pregnant.

Inclusion criteria for stroke group

male or female hemiparetic chronic stroke survivors;
age ranging between 40-75 year;
with single unilateral ischemic or hemorrhagic middle cerebral artery stroke;
neurologically stable for >6 months;
have an expectation that current medication will be maintained without changes for at least 3 months. Stable use of anti-spasticity medication (e.g., baclofen, diazepam, tizanidine) is accepted;
without severe spasticity (Modified Ashworth (MA) \<4);
have not received botulinum toxin on the impaired arm within 3 months.

Exclusion criteria for stroke group

have an orthopedic disorder involving upper limbs;
cognitive impairment sufficient to interfere with informed consent or successful completion of the protocol (Montreal Cognitive Assessment (MoCA) score \< 26);
a history of another neurologic disease;
anesthesia of joint position sense in upper limbs;
are pregnant or have a chance that they might be (self-reported);

University of Houston
Houston, TX 77204
Site contact: Jinsook Roh, PhD · 713-743-2578 · jroh@central.uh.edu