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Individual Cerebral Hemodynamic Oxygenation Relationships (ICHOR 1)

Children's Hospital Los Angeles · with National Heart, Lung, and Blood Institute (NHLBI) · NCT06195345

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Up to age 18 · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
1000
US sites recruiting
1
Study start
November 1, 2018
Record last updated
April 29, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

This is an observational study in patients who require clinical anesthesia. The main purpose of this study is to understand whether there are differences in the cerebral blood flow, and oxygen metabolism affected by different types of anesthesia. Subjects who require clinical anesthesia for a clinical MRI and for whom the use of anesthetics for the exam are in clinical equipoise are asked to join the study. All eligible subjects will be asked to provide informed consent before participating in the study.

Being studied: MR Imaging

Conditions: HIE; TBI (Traumatic Brain Injury); TBI; Hemodynamic Instability; Hypoxic-Ischemic Encephalopathy

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Individuals who are able to tolerate an MRI.
  • Are patients scheduled for a clinically indicated MRI.
  • Between birth and up to 18 years.

Exclusion Criteria

  • Presence of an MRI-incompatible device or implant (e.g. pacemakers, stents)
  • Unable to tolerate the enclosed spaces and loud noises for the duration of time in scanner required to obtain an MRI.
  • Preterm infants less than 25 weeks
  • Any patient who is clinically too unstable to extend their MRI by up-to 7.5 minutes.

Recruiting US locations

  • Children's Hospital Los Angeles

    Los Angeles, CA 90027

    Site contact: Gabriel Luna · 323-361-8791 · hspp@chla.usc.edu

Study contacts (from the official record)

  • Hannah E Wiseman, MPH · 323-361-3963 · hwiseman@chla.usc.edu
  • Matthew T Borzage, PhD · 323-601-5757 · mborzage@chla.usc.edu
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Individual Cerebral Hemodynamic Oxygenation Relationships (ICHOR 1) (NCT06195345) | Bored Studies