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Initial Testing of a Behavioral Intervention About Genetic Services for Families at Risk of Lynch Syndrome

University of Alabama at Birmingham · with National Cancer Institute (NCI) · NCT07106359

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18+ · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
185
US sites recruiting
1
Study start
September 15, 2025
Record last updated
July 21, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The purpose of the study is to see if our education materials help people at risk for Lynch syndrome decide about seeking genetic services. Untested relatives of patients with Lynch syndrome will be recruited to complete a baseline survey and will be randomized to receive either the an information letter or an information letter plus a booklet. Two follow-up surveys will be administered over the span of 6 months. Participants will also be invited to join an optional exit interview to provide feedback.

Being studied: Information Letter and Booklet; Information Letter

Conditions: Cascade Testing; Lynch Syndrome; Decision Making; Colorectal Cancer; Uterine Cancer; Cancer Prevention

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Probands Inclusion Criteria

  • English speaking
  • at least 18 years old
  • have had genetic testing for Lynch syndrome (LS)
  • do not have a condition that would interfere with their ability to provide informed consent and complete study activities (e.g., cognitive dysfunction evaluated using clinical judgment during screening)

Clinical Trial Participants Inclusion Criteria:

  • English-speaking
  • at least 18 years old
  • a blood relative of a patient who was diagnosed with LS
  • potentially at risk for LS
  • have not scheduled or had pre-test genetic counseling or genetic testing for LS
  • do not have a personal history of a cancer (excluding non-melanoma skin cancer)
  • do not have a condition that would interfere with their ability to provide informed consent and complete study activities (e.g., cognitive dysfunction evaluated using clinical judgment during screening)

Recruiting US locations

  • UAB

    Birmingham, AL 35233

    Site contact: study team · 205-914-2249 · LSPilotStudy@uabmc.edu

Study contacts (from the official record)

  • Haoyang Yan, PhD · 205-914-2249 · LSPilotStudy@uabmc.edu
  • Kaylee Burgan, MS · 205-914-2249 · LSPilotStudy@uabmc.edu
All healthy volunteers studies in Alabama →
Initial Testing of a Behavioral Intervention About Genetic… (NCT07106359) | Bored Studies