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Interventions in Mathematics and Cognitive Skills

Stanford University · with Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) · NCT05201534

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 6–12 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
180
US sites recruiting
1
Study start
May 5, 2023
Record last updated
August 11, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The purpose of this study is to investigate neurocognitive mechanisms underlying response to intervention aimed at enhancing, and remediating weaknesses in, numerical skills in children, including those with mathematical learning disabilities (MLD).

Being studied: Interventions in Mathematics and Cognitive Skills - Experimental; Interventions in Mathematics and Cognitive Skills - Active Comparator

Conditions: Math Learning Disability; Child Development; Developmental Disability; Learning Disabilities; Learning Disabled; Learning Curve; Mathematics Disorder; Dyscalculia; Dyscalculia, Primary; Dyscalculia, Acquired; Specific Learning Disorder, With Impairment in Mathematics; Individuality; Behavior, Child; Behavior and Behavior Mechanisms; Behavior; Decision Making; Neuronal Plasticity; Cognition; Cognition Disorder; Cognitive Dysfunction; Cognitive Change; Cognitive Impairment, Mild; Cognitive Developmental Delay; Cognitive Orientation; Cognitive Delay, Mild; Cognitive Deficits, Mild; Cognitive Abnormality; Neuroscience

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Elementary school aged children starting from first grade (6-12 years old)
  • IQ: Participants with a Full Scale IQ > 70 on the Wechsler Abbreviated Scle of Intelligence (WASI-II).
  • Identification of Mathematical Learning Disabilities: Scores below the 35th percentile percentile on symbolic number processing test in Numeracy Screener and two or more Wechsler Individual Achievement Test (WIAT-IV) math subtests
  • Identification of typically developing children: Scores at or above the 35th percentile percentile on symbolic number processing test in Numeracy Screener and all WIAT-IV math subtests
  • Normal or corrected-to-normal vision and no hearing impairments
  • Inclusion in MRI scan session: Right-handed

Exclusion Criteria

  • History of neurological or psychiatric disorder (i.e., schizophrenia, psychosis, depression, or attention deficit hyperactivity disorder.)
  • History of trauma involving head injury
  • Consistent psychiatric medications
  • Exclusion from MRI scan session: No major contraindication for magnetic resonance imaging (MRI) - braces, metal implants, pacemakers, vascular stents, metallic ear tubes, consistent exposure to metal, claustrophobia)

Recruiting US locations

  • Stanford Cognitive and Systems Neuroscience Laboratory

    Palo Alto, CA 94304

    Site contact: Zehra Unal · 737-615-0834 · zehraeu@stanford.edu

Study contacts (from the official record)

  • Vinod Menon, PhD · 16507363699 · menon@stanford.edu
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Interventions in Mathematics and Cognitive Skills (NCT05201534) | Bored Studies