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Ketone Monoester Supplements, High Altitude, and Brain Blood Flow During Exercise

McMaster University · NCT07063732

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–35 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
14
US sites recruiting
1
Study start
May 28, 2025
Record last updated
July 14, 2025

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The purpose of this trial is to investigate the effect of acute ketone monoester ingestion (0.6 g KME/kg body weight) on the occurrence of the ventilatory threshold and the subsequent response of blood velocity in cerebral arteries during a maximal exercise test at low altitude and high altitude.

Being studied: Ketone Monoester (KME); Placebo

Conditions: High Altitude Hypoxia; Exercise

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Must be a member of the research expedition team travelling to the Barcroft Research Station in White Mountain California

Exclusion Criteria

  • BMI > 30
  • No prescribed medications (oral contraceptives excluded)
  • History of smoking
  • Currently following a ketogenic diet or consuming exogenous ketogenic supplements
  • History of heart, lung, blood vessel, or kidney disease
  • Currently pregnant

Recruiting US locations

  • Barcroft Research Station

    Bishop, CA 93514

    Site contact: Jeremy Walsh, PhD · 9055259140 · walshj18@mcmaster.ca

Ketone Monoester Supplements, High Altitude, and Brain Blood Flow… (NCT07063732) | Bored Studies