Late Onset Alzheimer's Disease
Columbia University · with National Institute on Aging (NIA) · NCT05010603
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 55+ · All sexes
- Healthy volunteers
- Accepted
- Study type
- Observational
- Target enrollment
- 10000
- US sites recruiting
- 12
- Study start
- November 15, 2016
- Record last updated
- May 18, 2026
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
The goal of this study is to is to focus on the genetic influences on Alzheimer's Disease (AD) risk. The investigators are looking for families and/or individuals (affected or unaffected) of any ethic background (African American, Caucasian, and Hispanics) with a family history of AD and willing to participate.
Being studied: Blood Draw; Late Onset Alzheimer's Disease (LOAD) Neuropsychological Battery Test
Conditions: Alzheimer Disease
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Inclusion Criteria
- Established diagnosis of definite or probable AD or have a diagnosis of a related neurodegenerative disorder such as Frontotemporal Dementia (FTD) or Lewy Body Dementia (LBD) (will also recruit sporadic FTD and LBD) cases.
- a living sibling with probable or possible AD;
- a third living relative affected with AD (onset age 50 or older) or unaffected (60 or older);
- participants in the proband's generation with an identified companion serving as an informant;
- participants who have capacity to consent or participants lacking capacity to consent with a surrogate/proxy in place to provide consent.
Exclusion Criteria
- failure to identify an appropriate informant;
- uncertainty of the clinical diagnosis of Alzheimer's disease or other related disorder;
- discovery of additional diagnosis that could account for the clinical manifestations;
- unwillingness to participate;
- failure to identify a living sibling with AD or other related disorder (except in the cases of sporadic FTD and sporadic LBD);
- participants lacking the capacity to consent who do not have a surrogate or proxy or next of kin to provide consent.
Recruiting US locations
University of Washington
Washington D.C., DC 98105
Site contact: Sarah Payne
University of Miami
Miami, FL 33124
Site contact: Larry Deon
Rush University
Aurora, IL 60612
Site contact: Corey Woods
Indiana University
Bloomington, IN 47405
Site contact: Kelly Farber
NCRAD at Indiana University
Indianapolis, IN 46202
Site contact: Kelly Farber
Mayo Clinic
Rochester, MN 55901
Site contact: Christine Hanzel
Joanne Norton
St Louis, MO 63130
Site contact: Joanne Norton
Columbia University Irving Medical Center
New York, NY 10032
Site contact: Dolly Reyes-Dumeyer · 212-305-5953 · dr2290@cumc.columbia.edu
North Carolina State University
Raleigh, NC 27695
Site contact: Takiyah Starks
University of Pittsburgh
Pittsburgh, PA 15213
Site contact: Elise Weamer
University of Texas Southwestern
Dallas, TX 75390
Site contact: Amy Browning
University of Washington
Seattle, WA 98195
Study contacts (from the official record)
- Dolly Reyes-Dumeyer · 212-305-5953 · dr2290@cumc.columbia.edu
- Amanda Chan · 917-696-3082 · akc2177@cumc.columbia.edu
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