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Lung and Heart Function Across Decades of Life in Health

University of California, San Francisco · with US Department of Veterans Affairs · NCT07641413

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 24–68 · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
200
US sites recruiting
1
Study start
August 1, 2024
Record last updated
September 14, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The main objective of this study is to develop baseline "normal" reference values of both lung and heart function for healthy adults within the age range relevant to the United States Veteran population who served in the Southwest Asia theater of military operations.

This study will involve performing key components of the Department of Veterans Affairs the Airborne Hazards and Open Burn Pit Center of Excellence (AHOBPCE) and a VA network of Post-Deployment Cardiopulmonary Evaluation Network (PDCEN) Core Clinical Evaluation in asymptomatic unexposed healthy controls without known lung or heart disease to serve as a "normal" control comparator group for veterans evaluated by PDCEN.

Being studied: Healthy control

Conditions: Pollution Related Respiratory Disorder; Pollution; Exposure; Dyspnea; Cardiopulmonary

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Age 24-68
  • U.S. Veteran deployed between 1990 to 2021
  • No respiratory complaints (defined as modified Medical Research Council score = 0)
  • No use of respiratory medications

Exclusion Criteria

  • Non-English speaking
  • Pregnancy
  • BMI>35 Kg/m2
  • Tobacco smoking within prior year
  • Lifetime tobacco smoking of >5 pack-years
  • Current inhaled cannabis use (any modality) >2x weekly
  • Prior inhaled cannabis uses exceeding 2x weekly within the prior year
  • Illicit drug use (other than cannabis)
  • No prior or current major organ disease, including but not limited to:
  • Neuromuscular weakness
  • History of malignancy (other than non-melanoma skin cancer)-- HIV/AIDS
  • Autoimmune disease
  • Solid-organ or hematopoietic stem cell transplant
  • Cardiovascular disease (other than mild HTN; \< 140/90; controlled on 2 or less medications)
  • Poorly-controlled HTN (SBP>140 or DBP>90 or use of more than 2 anti-hypertensive medications)
  • Any history of congestive heart failure (CHF, either HFpEF or HFrEF)
  • Any history of arrythmia (including atrial fibrillation)

Recruiting US locations

  • University of California San Francisco

    San Francisco, CA 94143

    Site contact: Mehrdad Arjomandi, MD · 415-221-4810 · mehrdad.arjomandi@ucsf.edu

Study contacts (from the official record)

  • Mehrdad Arjomandi, MD · 415-221-4810 · mehrdad.arjomandi@ucsf.edu
All healthy volunteers studies in California →
Lung and Heart Function Across Decades of Life in Health (NCT07641413) | Bored Studies